人体免疫学  

出　　处：《中国学术期刊文摘》2009年第3期194-202,共9页Chinese Science Abstracts(Chinese Edition)

摘　　要：TNFR I封闭肽-IgGFc融合蛋白和TNFR I封闭肽对TNF-α介导的生物学效应的封闭作用;小鼠pⅣ启动子调控CⅡTA突变体重组腺病毒表达选择性抑制MHC Ⅱ类分子的表达;胸腺基质细胞支持下骨髓CD34^＋细胞向T细胞体外定向分化;TNFR1BP/hIgGIFc and TNFR1BP inhibit the biological effect mediated by TNF-α;The selective suppression of MHC Ⅱmolecule expression by recombinant adenovirus with mouse plV promoter-regulated C Ⅱ TA mutant;Human bone marrow CD34^＋ cells differentiate to T cells in thymic and bone marrow stromal microenvironment in vitro;Inhibition of Ki67 expression in human renal car-cinoma ACHN cells by oncolytic adenovirus harboring specific Ki67- siRNA leads to suppression of proliferation and induction of apoptosis

关 键 词：免疫学 CD34^+细胞 封闭作用 胸腺基质细胞 生物学效应 TNF-α 选择性抑制 重组腺病毒 

分 类 号：Q813.1[生物学—生物工程] S852.4[农业科学—基础兽医学]