茚虫威二种关键中间体的前驱体的合成研究  

Synthesis of Precursors of Two Key Indoxacarb Intermediates

作　　者：余生[1] 胡新根[1] 朱玉青[1] 陈帆[1] 

机构地区：[1]温州大学化学与材料工程学院,浙江温州325027

出　　处：《辽宁化工》2009年第2期77-80,共4页Liaoning Chemical Industry

基　　金：浙江省绿色化工技术重大科技专项(2006C11025)

摘　　要：在传统合成方法的基础上,分别以5-氯-1-茚酮和4-三氟甲氧基苯胺作为起始物,以绿色化学品碳酸二甲酯(DMC)作为甲氧羰基化试剂兼作溶剂来合成茚虫威二种关键中间体的前驱体。与传统的合成方法相比,该合成方法操作简便、安全,且收率较高,符合绿色合成的要求。On the basis of conventional synthesis methods, routes to precursors of two key intermediates of indoxacarb from 5 - chloro - 1 - indanone and 4 - trifluororoethoxy aniline respectively have been demonstrated, in which dimethyl carbonate （DMC） was served as roethoxyearbonylation reagent as well as solvent. The new approaches not only enable easier operation of synthesis, but also are more friendly to environment and of better yield than traditional methods.

关 键 词：茚虫威 5-氯-2-甲氧羰基-1-茚酮 4-三氟甲氧基苯基-氨基甲酸甲酯 碳酸二甲酯 前驱体 

分 类 号：O621.3[理学—有机化学]