T2DM冠脉病变与胆红素水平的关系  

作　　者：林玲[1] 壮可[1] 万颖[2] 李红[2] 李裕[2] 赵燕[1] 张宏[1] 

机构地区：[1]云南省第一人民医院心内科,650032 [2]云南省第一人民医院检验科

出　　处：《当代医学》2009年第4期70-71,共2页Contemporary Medicine

摘　　要：目的探讨2型糖尿病患者冠脉病变的程度与血清胆红素水平的关系。方法符合条件并经冠状动脉造影的糖尿病患者365例,根据其冠脉狭窄的程度分为5组,A组:无狭窄;B组:狭窄<50%;C组:狭窄在50%～79%;D组:狭窄在80%～99%;E组:完全闭塞。再将D+E组病人分为3组:单支、双支和三支病变组,均测定其血清胆红素水平。结果B～E组病人的总胆红素和间接胆红素水平明显低于A组,双支和三支病变组的各种胆红素水平均明显低于单支病变组(P<0.01),三支病变组的胆红素水平较双支病变组明显下降(P<0.01)。结论2型糖尿病患者血清胆红素水平可能与冠脉病变严重程度有相关性。Objective To investigate the relationship between severity of coronary artery disease and serum bilirubin in patients with type 2 diabetes mellitus.Methods 365 patients with type 2 diabetes mellitus who received coronary angiography were divided into 5 groups according to severity of coronary lesion： groupA： normal; group B： vessel stenosis〈50%; group C： vessel stenosis 50%-79%; group D： vessel stenosis 80%-99%; group E： total occlusion. All the patients in group D and group E were divided into 3 groups： single,double and triple vessel disease. Their serum bilirubins were measured. Results The TBIL and NDBIL level of group B-E were significantly lower than those of group A（P〈0.01）. Compared with single vessel disease group, the TBIL,DBIL and NDBIL of double and triple vessel disease group were declined significantly（P〈0.01）. Compared with double vessel disease group, all kinds of bilirubins in triple vessel disease group were decreased（P〈0.01）.Conclusion The severity of coronary artery disease had relationship with serum bilirubin in patients with type 2 diabetes mellitus.

关 键 词：2型糖尿病 冠脉病变 胆红素 

分 类 号：R541.4[医药卫生—心血管疾病]