尿铅、镉的石墨炉原子吸收光谱测定方法研究  

Study on the Method for Determination of Lead and Cadmium in Urine with Graphite Furnace Atomic Absorption Spectrometry

作　　者：郑丹[1] 陆慧萍[1] 张裕曾[1] 王晓宇(校对) 

机构地区：[1]华中科技大学公共卫生学院环境与健康教育部重点实验室,湖北武汉430030 [2]不详

出　　处：《环境与职业医学》2009年第1期65-69,共5页Journal of Environmental and Occupational Medicine

摘　　要：[目的]研究石墨炉原子吸收光谱法测定尿中铅、镉的方法。[方法]用石墨炉原子吸收光谱法以标准加入法模式对氯化钯等3种基体改进剂和石墨炉参数进行了优化选择，建立了用一套经同样处理的样品测定尿中铅、镉含量的方法。[结果]在所选实验条件下，铅的线性范围为0—60μg/L，加标回收率为96．81％～101．06％，检测限为0．0028μg/L，精密度相对标准偏差为0．97％～3．24％。镉的线性范围为0～3μg/L，回收率为99．02％～100．34％，检测限为0．0022μg/L，精密度测定相对标准偏差为0．68％-3．05％。[结论]建立的方法具有准确、稳定、灵敏、经济、简便等优点，能够满足铅和镉接触人群的健康监护和铅、镉中毒的诊断、治疗和疗效评价。[ Objective ] To study a method for determining lead and cadmium in urine using atomic absorption spectrometry. [ Methods ] Lead and cadmium in urine were determined by graphite furnace atomic absorption spectrometry on the pattern of standard additions, but optimized the matrix modifier and the parameters of graphite furnace. Under the condition, a method which could determine lead and cadmium only using one sample with the same treatment was set up. [ Results ] Under this conditions, the linear range of lead was at 0-60 μg/L, its recovery rate was 96.81%-101.06%, detecting limit was 0.002 8μg/L, and its relative standard deviation of precision was 0.97%-3.24%. The linear range of cadmium was at 0-3 μg/L, its recovery rate was 99.02%-100.34%, detecting limit was 0.002 2μg/L, and its relative standard deviation of precision was 0.68%-3.05%. [ Conclusion ] The method based on this sdudy was accurate, sensitive, cheap and convenient. It could be used for health supervision of the people who exposed to lead and cadmium, and also for diagnosis, treatment, therapeutic evaluation of toxic effect to human by lead or cadmium.

关 键 词：石墨炉原子吸收光谱法 尿 铅 镉 基体改进剂 

分 类 号：R115[医药卫生—公共卫生与预防医学]