新疆巴里坤地区哈萨克族9～10岁儿童动态血压及生化指标水平分析  

Ambulatory blood pressure and biochemical indicator analysis of 9-10 years old Kazakhstan Clan children in Xinjiang Baliken area

作　　者：徐新娟[1] 梁晓慧[1] 胡广梅[1] 毛新民[1] 泉样一[1] 小泽有纪雄[1] 张向阳[1] 地理夏提[1] 买买提[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心

出　　处：《中国组织工程研究与临床康复》2009年第7期1379-1382,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:了解新疆哈萨克族9～10岁儿童动态血压昼夜节律,测定其生化指标并与全国儿童的各参数水平相比。方法:选择新疆巴里坤地区9～10岁健康儿童49名,男27名,女22名;年龄(9.7±0.5)岁,身高(139.67±7.51)cm,体质量(30.91±6.15)kg,体质量指数(15.73±2.00)kg/m2。采用无创性携带式动态血压监测仪对受试者的动态血压进行监测,受试者集中居住48h,饮食自理,习惯照旧,正确收集24h尿量,询问病史和体检。抽空腹血分离血清,保存于-40℃深低温下待测。并将49名受试儿童动态血压的各项参数值和平均身高、体质量、体质量指数以及生化指标检测结果与全国儿童正常值相比较。结果:49名受试儿童均进入结果分析。①49名新疆哈萨克族9～10岁儿童24h动态血压平均值114/69mmHg(1mmHg=0.133kPa);白天血压平均值:125/78mmHg;夜间血压平均值:98/56mmHg。动态血压中最初2h的血压值为127/83mmHg,显著高于同等年龄的血压值(P<0.01)。②该地区儿童平均身高、体质量与全国同等地区、同等年龄、同性别的儿童相比均存在显著性差异(P<0.01)。③与全国儿童正常参考值相比,49名哈萨克族儿童血糖、三酰甘油、血肌酐、尿钠在正常范围内,血钠、血钾、总胆固醇、白蛋白、尿钾水平在正常值的下限,高密度脂蛋白、低密度脂蛋白与尿肌酐水平在正常参考值的上限。结论:新疆哈萨克族9～10岁儿童24h动态血压中最初2h的血压值较同等年龄的儿童高,部分血生化指标与全国儿童正常参考值有差异。AIM： To evaluate the 24 hour rhythm changes of ambulatory blood pressure of Kazakhstan Clan children in Xinjiang Baliken and to compare the biochemical indicators with the standardized parameter levels of China. METHODS： A total of 49 Kazakhstan Clan healthy children in Xinjiang Baliken area, including 27 boys and 22 girls, mean aged （9.7±0.5） years, （139.67±7.51） crn in height, （30.91±6.15） kg in weight with mean body mass index （8MI） of （15.73±2.0） kg/m2. A noninvasive portable ambulatory blood pressure monitor made in Japan was adopted. All subjects were centered dwelling for 48 hours, and maintained their habits. 24 hours＇ urine was collected. Venous blood samples of every child were drawn after an overnight fast, and then the samples were conserved in profound hypothermia （-40 ℃） for future measurement. Each parameter of the ambulatory blood pressure and the related biochemical indicators of the 49 children were compared with the standardized parameter levels in China. RESULTS： All the 49 children were included in the final analysis. （1）The mean blood pressure of 49 Kazakhstan Clan children in Xinjiang 8aliken was 114/69 mm Hg （1 mm Hg=0.133 kPa）, average blood pressure was 125/78 turn Hg at day time, and 98/56 mm Hg at night. The average initial 2 hours blood pressure was 127/83 mm Hg, which was significantly higher than that of the age-mated children （P 〈 0.01）. （2）The height and weight of the 49 children in this area were significantly different compared with that of national children of equal region, age and gender （P 〈 0.01）.（2）Compared with standardized parameter levels in China, the level of blood glucose, triglyceride, serum creatinine and urinary natriurn was normal, the level of serum sodium, serum kalium, total cholesterol, albumin, urine kalium was lower, but the contents of high density lipoprotein, low density lipoprotein, urine creatinine were higher than the limit of normal reference value. CONCLUSION： The average initial 2 h

关 键 词：儿童 动态血压测定 生化指标 正常参照值 

分 类 号：R181.3[医药卫生—流行病学]