北京地区部分人群接触密切的家畜(禽)戊型肝炎病毒感染血清学调查  

Antibody detection of hepatitis E virus in some human population, swine and chicken in Beijing in China

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作  者:田瑞光[1] 鲁健[1] 张博成[1] 江永珍[1] 毕胜利[1] 

机构地区:[1]中国疾病预防控制中心病毒病预防控制所,北京100052

出  处:《中华实验和临床病毒学杂志》2009年第1期14-16,共3页Chinese Journal of Experimental and Clinical Virology

摘  要:目的了解北京地区戊型肝炎(戊肝)病毒感染现状。方法采用EIA诊断试剂检测人群、猪和鸡血清中戊肝病毒(HEV)抗体。结果1208份人群血清中有260份HEV-IgG抗体阳性,总阳性率为21.52%,对260份HEV IgG阳性血进行IgM抗体检测,有22份阳性,占8.46%。32份猪血清中有15份阳性,阳性率为46.88%,34份鸡血清HEV抗体全部为阴性。人群不同年龄组HEV抗体阳性率依次为11~20岁为5.60%(14/250),21~30岁为20%(42/210),31~40岁为24.03%(62/258),41~50岁为26.44%(78/295),51~60岁为32.82%(64/195),男女不同性别HEV感染率比较,男性阳性率为29.51%(144/488),女性为21.70%(102/470)。结论北京地区人群和与人接触密切的家畜猪均存在戊肝病毒感染,人群戊肝病毒感染率随年龄增长而升高,尤其是男性戊肝病毒感染率明显高于女性,郊区流动人群戊肝病毒感染率明显高于市内人群,家畜猪感染率是人群的2倍以上。Objective To investigate the seroprevalenee of HEV infection in human population, swine and chicken in Beijing region. Methods EIA was used for detecting anti-HEV IgG of the serum samples. All samples were collected in 2006-2007 in Beijing areas. Results The anti-HEV IgG was detected positive in 21.52% of human (260/1208), 46.88 % (15/32) of swine, but was negative in chickens (0/24) . The positive rate of human at different age group, was 5.60% (14/250)of 11-20 year, 20% (42/210)of 21-30 year,24.03% (62/258)of 31-40 year, 26.44% (78/295) of 41-50 year, 32.82% (64/195)of 51-60 year. The male(29.51% ) was higher than the female (21.70%) . Conclusion The HEV infection was correlation with age and sex significantly. The infection rate was increased with age, the positive rate in swine was more double than the human population.

关 键 词:肝炎病毒 戊型 感染 抗体 病毒 血清流行病学研究 

分 类 号:R51[医药卫生—内科学]

 

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