肝硬化食管胃底静脉曲张破裂出血患者死亡事件的相关因素  

Related factors to in-hospital mortality in patients with gnstroesophageal variceal hemorrhage caused by liver cirrhosis

作　　者：靳权[1] 曲广[2] 

机构地区：[1]阜新市人民政府机关卫生所,辽宁阜新123000 [2]阜新市中心医院,辽宁阜新123000

出　　处：《现代医药卫生》2009年第5期663-664,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨食管胃底静脉曲张破裂出血(GEV)患者院内死亡事件的相关因素。方法:对因GEV入院患者的资料进行回顾性分析,研究相关的临床和实验室参数与患者院内死亡率的关系。结果:374例患者中有36例在院内死亡(占9.6%)。与存活患者相比,死亡患者的血清胆红素[44.5(18.8)vs25.7(8.6)μmol/L]、血清肌酐[203.3(123.8)vs97.2(44.2)μmol/L]水平及出现肝性脑病(PSE)的几率(50%vs20%)的差异具有统计学意义。死亡患者和存活患者内镜检查后24小时内再出血的发生率分别为44%和5%。结论:血清肌酐和胆红素水平、出现PSE及初次内镜治疗24小时内发生再出血是GEV患者死亡的相关因素。Objective：To investigate the factors related to in-hospital mortality in the patients with gastroesophageal varieeal hemorrhage.Methods：The records of the in-patients with gastro esophageal varieeal hemorrhage between January 2004 and December 2007 were retrospectively analyzed. The relevant clinical and laboratory parameters and their relationship to mortality were studied.Results：Of the 374 inpatients during the study period,36 （9.6%） died in hospital. Serum bilirubin [44.5（18.8）vs25.7（8.6）μmol/L] and serum creatinine [203.3（123.8）vs97.2（44.2） μmol/L] levels were higher among non-survivors than among survivors. Non-survivors were also more likely to suffer from PSE （50%） than survivors（20%）, while rebleeding within 24 h of endoscopy occurred in 44% and 5% of these groups, respeetively. Conclusion：Serum creatinine and bilirubin levels, presence of PSE, and rebleeding within 24 h of initial endoscopy are related to mortality in the patients with gastro esophageal varieeal bleeding.

关 键 词：食管胃底静脉曲张 死亡率 血清肌酐 血清胆红素 

分 类 号：R5[医药卫生—内科学]