糖尿病治疗过程中的临床难题——长期有效控制体重  

Does long-term effective control of body weight is a difficult problem in clinical of diabetes control.

作　　者：李强[1] 潘红艳[1] 

机构地区：[1]哈尔滨医科大学附属第二医院内分泌代谢病科,哈尔滨150086

出　　处：《中国实用内科杂志》2009年第3期215-217,共3页Chinese Journal of Practical Internal Medicine

摘　　要：糖尿病患者在控制血糖过程中,不论是应用胰岛素还是口服药物治疗,都容易引发体重的增加,无法做到长期有效控制体重。大量研究显示,随体重的增加糖尿病病死率也增加,特别是由于心血管疾病所造成的死亡。为降低病死率应长期有效控制体重,可以采用下列措施:(1)制定合理目标:一般每周减重0.5～1.0 kg为宜。(2)控制饮食:采用低热量、高蛋白、低脂肪的饮食。(3)运动治疗:推荐有氧运动。(4)药物干预治疗:使用二甲双胍或噻唑烷二酮类药物,对于严重肥胖的可以使用西布曲明或奥利司他。Weight increasing would happen with the control of glucose in diabetic patients, whether the application of insulin or that of oral medication. Long-term and effective weight control should be done in order to lower the mortality rate. A large number of studies have shown that the mortality rate has increased along with weight gain, especially death caused by cardiovascular disease. The following measures can be used： （ 1 ） Rational target should be formulated. It would be the best that weight decrease 0. 5 - 1.0 kg every week. （2） Diet should be controlled. Low-calorie, high protein, low-fat diet can be used. （3）Exercise therapy：Aerobic exercise will be recommended. （4）Drug intervention treatment： Metformin or Thiasolidinediones drugs can be use, Sibutramine or Orlistat can be used in the patients with serious obesity.

关 键 词：体重 糖尿病 心血管疾病 

分 类 号：R5[医药卫生—内科学]