糖脑络通联合低能量氦氖激光血管内照射对糖尿病脑梗死患者血流变及内皮素的影响  

Effect of Tangnaoluotong Combined with Intravenous Low Intensity Laser Irradiation on Blood Rheology and Endothelin of Diabetes Mellitus and Cerebral Infarction Patients

作　　者：王波[1] 何珂[1] 魏海峰[2] 刘喜明[3] 倪青[3] 林兰[3] 

机构地区：[1]中国人民解放军总医院第二附属医院,北京100091 [2]首都医科大学宣武医院,北京100053 [3]中国中医科学院广安门医院,北京100053

出　　处：《中国中医药信息杂志》2009年第3期10-11,89,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(696448001)

摘　　要：目的观察中药糖脑络通联合低能量氦氖激光血管内照射治疗对糖尿病脑梗死患者血液流变学指标及内皮素水平的影响。方法将确诊为糖尿病并脑梗死、中医辨证属气阴两虚兼夹血瘀型的90例患者随机分为3个治疗组:激光组、中药组(糖脑络通)和激光+中药组,观察治疗1个月后血液流变学、内皮素的变化。结果治疗后,激光+中药组能显著降低血中内皮素、纤维蛋白原水平,提高红细胞变形能力,疗效优于激光组和中药组。结论糖脑络通联合低能量氦氖激光血管内照射能明显改善糖尿病并脑梗死患者的血液流变学和内皮素水平,从而更好达到治疗目的。Objective To observe the effect on the patients of diabetes meUitus and cerebral infarction in terms of level of blood rheology and endothelin after using both intravenous low intensity laser irradiation （ILILI） and traditional Chinese medicine Tangnaoluotong in the treatment. Method Ninety patients of diabetes meUitus and cerebral infarction, having the symptom of deficiency in both vital energy and yin with blood stasis, were divided into three treatment groups at random： ILILI group （A）, TCM treatment group （B）, and a group with compound treatment of ILILI and TCM （C）. The level of blood rheology and endothelin were observed after 1 month＇s treatment. Result Compared with group A and group B, group C could significantly reduce the level of fibrinogen and endothelin, improve the deformed ability of RBC. Conclusion ILILI with Tangnaoluotong can significantly alter the blood rheology and endothelin on the patients of diabetes mellitus and cerebral infarction, which result in a better curative effect.

关 键 词：糖脑络通 低能量氦氖激光血管内照射 糖尿病 脑梗死 血液流变学 内皮素 

分 类 号：R259.872[医药卫生—中西医结合]