甲基膦酸二乙酯分子印迹聚合物的合成与识别特性研究  

Study on Synthesis and Recognition Characteristic of Diethyl Methylphosphonate Molecularly Imprinted Polymer

作　　者：赵冲林[1] 陈志升[1] 魏崇禧[1] 龚丹[1] 

机构地区：[1]防化研究院,北京102205

出　　处：《分析测试学报》2009年第1期84-87,92,共5页Journal of Instrumental Analysis

摘　　要：合成了能有效识别甲基膦酸二乙酯及其同系物的分子印迹聚合物,对比了氘代溶液中甲基膦酸二乙酯在加入功能单体前后31P{H}NMR谱测定结果的变化,因分子间氢键的作用,磷的化学位移由30.288移动到32.699。用Scatchard模型表征了分子印迹聚合物的结合特性,得到平衡离解常数Kd=0.74mg/L,最大表观结合量Qmax=112.25μg/g。用静态吸附分配系数Kp和识别因子α表征了其选择特性。将该分子印迹聚合物用于固相萃取的吸附材料,进行了8种模板分子相似物的有效分离。A series of molecularly imprinted polymers （MIPs） were prepared using diethyl meth- ylphosphonate（DEMP） as template. The function of H-bond between the template molecule and functional monomer was discussed by comparing the difference of 31p { H } NMR. After functional mono- mer being added, the chemical shift of phosphor was changed from 30. 288 to 32. 699. The binding characteristics of MIPs were evaluated with Scatchard plot, in which the equilibrium dissociation constant K, was calculated to be 0.74 mg/L, and the apparent maximum number Q was calculated to be 112.25μg/g. The selective recognition of DEMP-MIPs were characterized by static adsorption dis- tribute coefficient Kp, and recognition factor a. DEMP-MIP, as a selective sorbent in solid phase extraction（SPE） , was successfully applied in the separation of 8 analogs.

关 键 词：分子印迹聚合物 固相萃取 氢键 分子识别 

分 类 号：E929[军事—军事装备学] O652.6[兵器科学与技术—武器系统与运用工程]