肥胖女大学生减肥前后血脂成分及内分泌激素的变化  

RESEARCH ON CHANGES OF LIPID COMPOSITION AND ENDOCRINE HORMONE BEFORE AND AFTER WEIGHT REDUCTION OF OBESE FEMALE COLLEGE STUDENTS

作　　者：王小引[1] 王俐[1] 傅兰英[2] 

机构地区：[1]新乡医学院生物化学与分子生物学教研室,新乡453003 [2]新乡医学院体育系

出　　处：《现代预防医学》2009年第5期843-845,共3页Modern Preventive Medicine

基　　金：2003年全国教育科学"十五"规划教育部重点课题(批号:DLA030208);2005年河南省教育厅资助项目(2005-ZX-405)

摘　　要：[目的]观察综合减肥方法对单纯性肥胖女大学生血脂成分及相关激素的影响及机制,为教育系统建立有效可行的青少年肥胖干预措施提供科学依据。[方法]将60名肥胖女大学生随机分为实验组和对照组,实验组学生实施为期10个月的综合减肥试验,观察减肥前后身体形态、血脂成分、血胰岛素、瘦素、皮质醇的变化。[结果]经过10个月的减肥试验,实验组肥胖女大学生体重、体重指数、体脂百分比、腰围、臀围较实验前明显降低(P﹤0.05),血脂成分改变即TG、TC、LDL-C和apoB100含量显著性下降,HDL-C、apoAI较实验前明显升高(P﹤0.05);血胰岛素和瘦素水平明显降低,皮质醇含量明显升高(P﹤0.01)。[结论]长期系统的合理减肥方法能使肥胖女大学生体重降低、体脂减少,身体成分趋于合理化,血脂成分改变,血脂中各成分的比例更有利于健康,并可起到调节异常内分泌代谢的作用。[Objective] To explore effect of reducing fat on the lipid composition and relative hormone and its mechanism of obese female college students, and give some advice to parents and education division. [Methods] Sixty obese female college students were equally divided into experiment group and control group. Experiment group was carried out comprehensive measures of reducing fat for ten months. Then the changes of body shape, lipid composition, blood lipid, insulin, leptin and cortisol of obese female college students were examined before and after experiment. [Results] After experiment, the weight, BMI, percentage of body fat, waist circumference, hip circumference in experiment group were obviously lower comparing with those before experiment （P﹤0.05）. The level of TG, TC, LDL-C and apoB100 decreased significantly, but HDL-C, apoAI increased significantly （P﹤0.05）. The level of leptin and insulin descended greatly while cortisol raised remarkably （P﹤0.01）. [Conclusion] Long-term comprehensive measures of reducing fat can reduce their weight and fat, rationalize their body composition, and change the lipid composition, the percentage of which benefits their bodies, and meanwhile, it can adjust the metabolism disorder.

关 键 词：减肥 肥胖 女大学生 血脂 激素 

分 类 号：R589.2[医药卫生—内分泌]