硫酸软骨素、西乐葆及莫比可治疗成人大骨节病效果观察  

EFFECT OBSERVATION OF TREATMENT OF KASCHIN-BECK DISEASE WITH CHONDROITIN SULFATE,CELECOXIB CAPSULES AND MOBIC

作　　者：李富忠[1] 邓佳云[1] 黄慧[1] 陈开华[2] 张林[1] 

机构地区：[1]四川省疾病预防控制中心,成都610041 [2]四川省阿坝州疾病预防控制中心

出　　处：《现代预防医学》2009年第5期936-937,952,共3页Modern Preventive Medicine

基　　金：中央补助地方公共卫生专项资金地方病防治项目(2006)

摘　　要：[目的]观察硫酸软骨素、西乐葆及莫比可3种药物治疗成人大骨节病的临床疗效,为大骨节病病区患者筛选高效、安全的对症治疗药物提供科学依据。[方法]选择35～60岁有症状的大骨节病患者240人,分为3组,分别给予口服硫酸软骨素、西乐葆及莫比可,根据其治疗前后的WOMAC指数变化情况判断治疗效果。[结果]经过治疗6个月后,硫酸软骨素、西乐葆和莫比可对减轻患者症状及改善关节功能有效率分别为74%、98%和97.5%。[结论]硫酸软骨素治疗成人大骨节病对改善病情有一定的疗效,西乐葆和莫比可对改善大骨节病患者自觉症状及减轻疼痛具有肯定的止痛效果。[Objective] To observe the clinical efficacy of treatment of adult KBD with Chondroitin sulfate, Celecoxib capsules and Mobic, so as to provide a scientific basis for selecting efficient and safe symptomatic treatment drugs for patients in Kashin-Beck disease area. [Methods] Chose 240 cases of 35 to 60-year-old Kashin-Beck patients, divided into three groups, gave oral Chondroitin sulfate, Celecoxib capsules and Mobic respectively. According to Western Ontario and McMaster Universities （WOMAC）, changes of osteoarthritis index before and after treatment were analyzed to judge the therapeutic effect. [Results] After six months of treatment, Chondroitin sulfate, Celecoxib capsules and Mobic reduced symptoms and improved joint function, their efficient rate was 74%, 98% and 97.5% respectively. [Conclusion] Chondroitin sulfate has a certain effect on improving patient’s condition, Celecoxib capsules and Mobic have an affirmative effect on improving symptoms and reducing pain in treatment of adult KBD.

关 键 词：硫酸软骨素 大骨节病 效果 观察 

分 类 号：R684.1[医药卫生—骨科学]