念珠菌性包皮龟头炎的菌种分布及其药敏试验分析  

Investigation on Species and Drug Susceptibility Of the Clinic lsolates from Candidal Balanoposthitis

作　　者：潘伟光[1] 钟海萍[1] 张建华[1] 周天祥[1] 李江[1] 

机构地区：[1]广东医学院附属深圳南山医院,广东深圳518052

出　　处：《岭南皮肤性病科杂志》2009年第1期33-35,共3页Southern China Journal of Dermato-Venereology

摘　　要：目的:了解念珠菌性包皮龟头炎的致病菌种及其对抗真菌药物的敏感性。方法:分别采用沙保罗琼脂平板、法国生物梅里埃公司的酵母样真菌鉴定卡(ID 32C)、酵母样真菌药敏卡(ATB FUNGUS3)对包皮龟头分泌物进行念珠菌的培养、鉴定和药敏试验。结果:1 227例患者共培养出356株念珠菌,阳性率为29.0%。其中,白色念珠菌297株(83.5%)、光滑念珠菌41株(11.5%)、热带念珠菌14珠(3.9%),其它念珠菌4株(1.1%)。白色念珠菌和光滑念珠菌对5-氟胞嘧啶、两性霉素B、氟康唑、伊曲康唑、伏立康唑的敏感率分别为98%、100%、97.3%、61.3%、100%和95.1%、100%、19.5%、12.2%、95.1%。结论:白色念珠菌是念珠菌性包皮龟头炎的主要致病菌种,不同菌种对药物的敏感性有所不同。Objective：To investigate the pathogenetic species of yeast in candidal balanoposthitis and thesusceptibility Of candida spp againt antifungal agents. Methods：Sabouraud agar plate, France Biomerieux yeast - like fungi identification card （ ID32C ） and yeast - like fungi drug susceptibility card（ ATB FUNGUS 3 ）were applied to culture and identify candida strains and for yeast susceptibility testing. Results：356 cases（29.0% ） were cultured positive for candida in 1227 patients. 297 of 356 isolates （83.5 % ）were candida albieans,41 of 356 （11.5 % ）isolates were candida glabrata, 14 of 356（3.9% ）isolates were candida tropicalis, 4 of 356 （1.1% ）were other eandida species. Drug susceptibility rate of candida albicans and candida glabrata to fiucytosine, amphotericin B, fiuconazole, itraeonzole, mieonazole, voriconazole were 98.0% ,100% ,97.3% ,61.3% ,100% ;95.1%, 100%, 19.5 %, 12.2% ,95.1% respectively. Conclusion ： Candida albican was the main species pathogeneous yeast of candidal balanoposthitis, the result shows drug susceptibility rate of different candida speciesare different.

关 键 词：念珠菌 包皮龟头炎 药敏试验 

分 类 号：R697.1[医药卫生—泌尿科学] R446.5[医药卫生—外科学]