腹膜透析患者钙磷代谢紊乱的探讨  

To Explore the Disorders of Calcium and Phosphorus Metabolism in Peritoneal Dialysis Patients

作　　者：翁敏 白云凯[1] 杨荆[1] 

机构地区：[1]昆明医学院第一附属医院肾脏内科,云南昆明650032

出　　处：《昆明医学院学报》2009年第1期77-79,共3页Journal of Kunming Medical College

基　　金：云南省教育厅资助项目(5Y0468C)

摘　　要：目的探讨持续不卧床腹膜透析(CAPD)患者残肾功能和腹透充分性对钙磷代谢的影响.方法43例CAPD患者测定其血清钙、磷、白蛋白及甲状旁腺激素(PTH)的水平.所有患者以尿素清除指数(Kt/v)1.7和肌酐清除率Ccr50L/(周173m)2作为透析充分性的最低标准.结果无残肾功能患者的血磷及钙磷乘积较有残存肾功能患者明显升高(P<0.05);透析充分的患者与不充分者比较,血钙、血磷及钙磷乘积差异无统计学意义.结论CAPD患者普通存在钙磷代谢紊乱,以钙磷乘积及血磷升高较明显,残存肾功能对血磷的清除起着重要的作用.Objective To investigate the influence of residual renal function and adequacy of peritoneal dialysis on the calcium and phosphorus metabolism in continued ambulatory peritoneal dialysis patients （CAPD）. Method The serum calcium,serum phosphate,albumin and parathyroid hormone of 43 CAPD patients were detected.The adequacy of the CAPD patients was set a target minimum Urea kt/v of 1.7 and total weekly Ccr of 50L.Results The patients who had not residual renal function had significant elevated serum phosphate level and value of[ca2＋]×[p3＋]（P〈0.05）.The levels of serum calcium,serum phosphate and calcium-phophorus product were not remarkable difference in adequate and inadequate CAPD patients.Conclusion Disorder of calcium and phosphorus metabolism,especially higher serum phosphate and higher calcium-phosphorus product is universal in CAPD Patients.The residual renal function plays an important role in the clearance of serum phosphate.

关 键 词：腹膜透析 钙磷代谢 残肾功能 

分 类 号：R692.5[医药卫生—泌尿科学]