儿童神经母细胞瘤颅面骨转移的影像表现  

The imaging find＇ngs of metastatic neuroblastoma in the craniofacial bone in children

作　　者：边昕[1] 王振常[1] 鲜军舫[1] 李眉[1] 燕飞[1] 陈青华[1] 杨本涛[1] 常青林[1] 田其昌[1] 刘中林[1] 

机构地区：[1]首都医科大学附属北京同仁医院影像中心,100730

出　　处：《中华放射学杂志》2009年第3期258-261,共4页Chinese Journal of Radiology

摘　　要：目的探讨儿童神经母细胞瘤颅面骨转移的影像表现。方法回顾性分析12例经组织学证实的儿童神经母细胞瘤的影像表现。其中10例患儿行CT平扫，6例行MRI，7例行全身SPECT骨扫描。结果行CT检查的10例患儿中，9例表现为颅面骨溶骨性骨质破坏伴软组织肿块，其中8例可见骨膜反应，3例表现为特征性的针状骨膜反应；另1例CT未发现异常但骨扫描显示异常。行MR检查的6例患儿均表现为颅面骨骨髓腔信号异常伴周围软组织肿块，其中5例行增强扫描，骨髓腔异常信号影和软组织肿块呈明显不均匀强化。7例行全身骨扫描，均可见颅面部放射性浓聚区，其中6例伴有全身其他部位的骨转移。结论神经母细胞瘤颅面骨转移有一定的影像特征，可提示诊断。Objective To investigate the characteristic imaging findings of metastatic neuroblastoma in the craniofacial bone in children. Methods Imaging findings in 12 patients with metastatic neuroblastoma in the craniofacial bone were analyzed retrospectively. Among them, 10 patients underwent plain CT scan, 6 underwent MRI and 7 underwent whole body single-photon emission computed tomography bone scanning. Results In the 10 patients with CT images, lytic bone destruction and soft tissue masses were found in 9 cases, in which periosteal reaction was observed in 8 patients with spiculated periosteal reaction in 3 patients. The remaining 1 patient didn＇t show any abnormalities on CT images but had abnormal findings in bone scanning. Six patients with MR images showed abnormal signal intensity in the bone marrow of the craniofacial bone and adjacent soft tissue masses. Postcontrast T1-weightea imaging in 5 patients demonstrated remarkable enhancement of the bone marrow and soft tissue masses. Bone scanning of 7 patients showed abnormal loci of increased radionuclide activity of the craniofacial bone in 7 patients and metastasis at other body parts in 6 patients. Conclusion The metastatic neuroblastoma in the craniofacial bone has its characteristic imaging findings which are helpful for correct diagnosis.

关 键 词：神经母细胞瘤 头颈部肿瘤 诊断显像 儿童 肿瘤转移 

分 类 号：R686[医药卫生—骨科学]