特应性皮炎的免疫学发病机制  

Immunological Pathogenesis of Atopic Dermatitis

作　　者：吴忠[1] 李宏[1] 

机构地区：[1]江苏大学附属医院风湿免疫科

出　　处：《中华临床免疫和变态反应杂志》2008年第4期291-296,共6页Chinese Journal of Allergy & Clinical Immunology

摘　　要：特应性皮炎是慢性复发性炎症性皮肤疾病,发病机制复杂,其中变态反应因素在发病机制中扮演着重要角色。目前认为Th1/Th2平衡失调是特应性皮炎重要的发病机制。本文围绕这一机制综述T细胞、树突状细胞、角质形成细胞及IgE在特应性皮炎发病机制中的作用。dermatitis （AD） is a chronic recurrent and inflammatory skin disease with a complicated pathogenesis. Allergic reaction plays an important role in the development of AD. The immune effector T cell is approved to be a key role in the pathogenesis of AD. In this article, the functions of T cell, dentric cell, glial cell, and IgE were reviewed in the pathogenesis of AD.

关 键 词：特应性皮炎 T细胞 树突状细胞 角质形成细胞 

分 类 号：R392.8[医药卫生—免疫学]