新工人棉尘暴露5年气道反应性的改变  

Longitudinal study on airway responsiveness of new cotton workers

作　　者：马庆晏[1] 李德鸿[1] 

机构地区：[1]中国预防医学科学院劳动卫生与职业病研究所

出　　处：《中华劳动卫生职业病杂志》1998年第2期103-105,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：目的研究棉尘对工人气道反应性的影响。方法对一组接尘新工人进行了５年的前瞻性观察。结果暴露后激发试验ＦＥＶ１的下降率平均在３％～５％之间，均大于暴露前的下降率。吸烟与特异体质两因素在暴露早期对气道反应性的增高有促进作用。激发试验ＦＥＶ１下降率＞５％及＞１０％者随暴露时间延长呈逐年上升趋势，且在第５年出现１例＞２０％者。结论棉尘职业暴露可引起新工人气道反应性的增高。To study the effect of cotton dust on bronchial responsiveness of workers,60 new cotton workers were followed up for 5 years since they started exposure.Methacholin chloride bronchial provocation test was performed before and after exposure in 10 weeks,1 year,3 year and 5 year.FEV1 decreased about by 3%￣5% in average after exposure.There were more workers showed FEV1 decline of more than 5% and 10% as exposure went on.In the 5th year,one worker showed FEV1 decline of more than 20% after methacholin challenge.It is suggested that exposure to cotton dust may increase airway responsiveness in new workers.Smoking and atopic status may be the risk factors.

关 键 词：粉尘危害 棉尘 新工人 气道反应性 

分 类 号：R135.2[医药卫生—劳动卫生]