亲属脾移植术后移植物抗宿主反应和移植脾亢的成功治疗经验  

Successful treatment of graft versus host reaction and graft hypersplenism after relative spleen transplantation

作　　者：陈知水[1] 夏穗生[1] 于昌松[1] 曾凡军[1] 刘慎微[1] 刘敦贵[1] 张伟杰 

机构地区：[1]同济医科大学附属同济医院器官移植研究所

出　　处：《中华器官移植杂志》1998年第2期92-93,共2页Chinese Journal of Organ Transplantation

基　　金：卫生部科研基金

摘　　要：移植物抗宿主反应（ＧＶＨＲ）和移植脾亢是脾移植的两个棘手问题。因二者来势凶猛，控制困难，既往治疗常是切除移植脾脏。我们介绍一例父亲供脾移植术后７天和２１天发生ＧＶＨＲ和移植脾亢。There are two knotty problems in spleen transplantation, graft versus host reaction (GVHR) and graft hypersplenism, which are very dangerous and uncontrolled. The previous treatment was to remove the spleen graft. Presented in this paper was one case of relative (father to son) spleen transplantation for treating hemophilia A. GVHR and hypersplenism occurred on 7th day and 21st day after transplantation. Satisfactory therapeutic effect was obtained through the region irradiate with deep Xray and Co60 respectively.

关 键 词：脾移植 移植物 抗宿主反应 移植脾亢 亲属脾 

分 类 号：R657.605[医药卫生—外科学] R392.4[医药卫生—临床医学]