普通人群精液质量与血清生殖激素水平的典型相关分析  

The Canonical Correlation Analysis on the Semen Quality and Serum Hormone among Normal Chinese Male Adults

作　　者：崔元起[1] 高尔生[2] 周维谨[2] 武俊青[2] 袁伟[2] 

机构地区：[1]上海市人口和计划生育委员会,200003 [2]上海市计划生育科学研究所,200032

出　　处：《中国卫生统计》2009年第1期55-57,59,共4页Chinese Journal of Health Statistics

基　　金：国家人口和计划生育委员会资助(项目编号:9902)

摘　　要：目的探索血清生殖激素(FSH、LH、T、E2)水平与中国普通成年男性精液质量指标之间的相关关系。方法研究对象为中国5省20～59周岁一般成年男性978名。常规手工精液检测,放射免疫分析法测定生殖激素,对两组变量进行典型相关分析。结果调整地区和禁欲时间因素后,FSH、E2与各精液质量指标之间均无相关关系;LH与精子存活率和正常精子形态率均呈负相关;T与精子存活率呈正相关,与精子密度和前向运动精子率是负相关关系。精液质量与血清生殖激素两组指标间典型相关关系显著,分析发现睾酮与精子存活率呈正相关关系,与前向运动精子率以及精子密度呈负相关关系;LH与精子存活率呈负相关。结论精液质量指标与血清生殖激素典型相关明显,T和LH分别与相关精液指标有显著相关关系。Objective To explore the correlation between the serum hormone （FSH,LH, T, E2）and semen parameters among nonmal Chinese male adults. Methods The study population consisted of 978 male volunteers from 5 provinces of China whose ages were from 20 to 59. Semen quality was analyzed on site and the serum concentrations of FSH, LH, T, and E2 were tested using RIA. The relationships between reproductive hormones （ FSH, LH, T, and E2 ） and sperm quality, including sperm volume, density, viability, mobility and morphology, were analyzed used Spearman rank correlation and canonical correlation. Results Under confounding controls for age and abstinence time, FSH and E2 show no significant correlation with any semen quality variable; LH has a negative correlation with sperm livability and normal morphology sperm; T has a positive correlation with sperm livability but a negative correlation with semen density and normal morphology sperm. Canonical correlation analysis also found T has a negative correlation with sperm motility and semen density and a positive correlation with sperm livability, LH has a negative correlation with sperm livability. Conclusion Canonical Correlal significant. T and LH have respectively.

关 键 词：精液质量 生殖激素 典型相关分析 

分 类 号：R698.2[医药卫生—泌尿科学] R446.1[医药卫生—外科学] R817.4[医药卫生—临床医学]