电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响  

Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats

作　　者：司全明[1] 吴根诚[1] 曹小定[1] 

机构地区：[1]上海医科大学医学神经生物学国家重点实验室,上海200032

出　　处：《针刺研究》1998年第1期36-40,共5页Acupuncture Research

摘　　要：本实验在大脑中动脉阻塞（MCAO）及再灌注动物模型上，观察缺血后电针对大鼠体感诱发电位（SEP）和脑梗塞体积的影响。结果发现缺血组和缺血后电针组在MCAO后30分钟，缺血侧SEP波幅降至缺血前的2．2±3％，1．9±2％，缺血后再灌注7天，SEP恢复至缺血前的25．5±14．1％，58．6±27．2％，两组比较P＜0．05；脑梗塞体积分别为70．72±25．4mm3，45．65±11．4mm3（P＜0．05）。结果提示电针可促进脑缺血后SEP的恢复，减少脑缺血性组织坏死。The model of reversible middle cerebral artery occlusion(MCAO) was used to study the effect of electroacupuncture(EA) on somatosensory evoked potential (SEP) and infarct volume after MCAO in rats. After 1 hour of MCAO, EA was applied at the points of Fengfu(DU 16)and Renzhong(DU 26).The results were as follows: (1) In MCAO group and MCAO + EA group the amplitude of SEP on the ipsilateral side of MCAO was nearly abolished at 30 min after MCAO and recovered to 25.5±14.1%,58. 6±27. 2 % (P <0.05)on day 7 after reperfusion. (2) The infarct volume in MCAO group and EA + MCAO group was 70. 72±25. 4mm3, 45. 65±11. 4mm3 (P <0.05) respectively after reperfusion 7 days following MCAO 2 hours.The results above indicate that EA might produce cerebroprotective effect after focal cerebral ischemia.

关 键 词：脑缺血 体感诱发电位 脑梗塞 体积 电针 

分 类 号：R245.97[医药卫生—针灸推拿学] R277.733[医药卫生—中医临床基础]