急性HIV感染及其检测技术研究进展  

Acute HIV infection and progress on detection techniques

作　　者：彭锐锐[1] 陈祥生[1] 

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所,南京210042

出　　处：《国际流行病学传染病学杂志》2009年第1期42-45,共4页International Journal of Epidemiology and Infectious Disease

摘　　要：艾滋病已成为世界范围内重要的公共卫生问题。既往发现HW感染者的方法主要是基于对HIV抗体的检测，然而，在HIV感染至抗体检测阳性这一急性Hrv感染（AHX）阶段，患者体内具有一过性的高病毒血症，传染性极强。开展AHI的筛查，及时发现AHI者并给予有效的干预和治疗可以防止H1V的进一步传播，减缓感染者的病程，具有个体临床和群体公共卫生的双重意义。此文综述了AHI的概念、临床表现、流行病学意义以及相应的检测技术进展和费用等。HIV/AIDS has become an important public health problem throughout the world. HIV infection is usually detected through a positive antibody test. However, during the period of time between initial infection and the antibody test to register a positive result, an individual may be highly infectious in a high level of virusemia. This period,known as acute HIV infection （A HI）, necessitates a different mode of H1V screening in order to improve detection, treatment and reduce HIV transmission. There is clinical and public health significance. In the current review, the concept, clinical manifestation and epidemiological significance of AHI as well as advances in early detection during this period is introduced.

关 键 词：HIV 急性感染 样本集合 RT-PCR P24抗原 

分 类 号：R51[医药卫生—内科学]