蒙古族原发性高血压前期与原发性高血压危险因素聚集  

Comparison of Risk Factors Clustering Between Prehypertensives and Essential Hypertensives Among Mongolian Population

作　　者：张明芝[1] 布仁巴图[2] 李红美[1] 林哲[2] 李永山[3] 张显玉[4] 佟伟军[1] 张永红[1] 

机构地区：[1]苏州大学医学部放射医学与公共卫生学院流行病学教研室,江苏苏州215123 [2]通辽市疾病预防控制中心,内蒙古通辽028000 [3]内蒙古科左后旗疾病预防控制中心,内蒙古通辽028000 [4]内蒙古奈曼旗疾病预防控制中心,内蒙古通辽028000

出　　处：《中华高血压杂志》2009年第3期260-263,共4页Chinese Journal of Hypertension

基　　金：国家自然科学基金项目(批准号:30471484)

摘　　要：背景蒙古族居民高血压前期是否存在危险因素聚集尚不明了。目的比较蒙古族高血压前期与原发性高血压(EH)之间饮酒、超重或肥胖、高血脂和高血糖的聚集水平。方法以2537名20岁及以上蒙古族居民为研究与分析对象,调查收集人口统计学、生活方式资料,测量血压、身高、体质量、腰围和臀围,并检测血糖、血脂等指标。分析比较高血压前期和EH之间危险因素聚集的差异以及危险因素聚集与高血压前期和EH的关联强度。结果平均年龄、三酰甘油、总胆固醇、低密度脂蛋白胆固醇、空腹血糖、体质量指数、腰围、收缩压、舒张压水平以及男性的比例、饮酒率、高血压家族史和高血糖暴露率均为EH>高血压前期>血压正常(均P<0.01)。调整年龄、性别后,饮酒、超重或肥胖、高血脂和高血糖4种危险因素的聚集与高血压前期和EH的危险性相关联。高血压前期病人危险因素聚集项数为1、2、3或4的OR值(95%CI)分别为1.40(1.10～1.76)、1.53(1.12～2.09)、3.75(2.12～6.63);EH病人危险因素聚集项数1、2、3或4的OR值(95%CI)分别为1.65(1.26～2.17)、4.17(3.01～5.77)、9.51(5.36～16.86)。结论在蒙古族人群,高血压前期就存在着危险因素的聚集现象。为预防EH和其他心血管病,对高血压前期实施干预措施是十分必要的。Background Data regarding clustering of cardiovascular risk factors in stage of prebypertension in Mongolian are paucity. Objective To compare clustering of alcohol drinking, overweight or obesity, hyperlipidemia and hyperglycemia between prehypertensives and essential hypertensives（EH）. Methods A cohort of 2537 Mongolian people aged 20 years or more were recruited. Demographic data, lifestyle and family history of EH were collected. Blood pressure, height, weight, waist circumference and hip circumference blood glucose and lipids were examined for all individuals. Difference for risk factors clustering between prehypertensive and EH was compared, and associations between risk factors clustering and prehypertension and EH were analyzed. Results Age, triglyceride, total cholesterol, low density lipoprotein cholesterol, fasting plasma glucose, body mass index, waist circumference, SBP, DBP were higher in hypertensives than that in prehypertensive（all P〈0.01）. After age and sex were adjusted, prehypertension and EH were associated with clustering of alcohol drinking, overweight or obesity, hyperlipidemia and hyperglycemia. For patients with prehypertension, age and gender-adjusted ORs of clustering of one, two and three or four factors were 1.40（1.10-1.76）, 1.53（1.12-2.09） and 3.75（2.12-6. 631, respectively. For patients with EH, age and gender-adjusted ORs of clustering of one, two and three or four factors were 1.65（1.26-2.17）, 4.17（3.01-5.77） and9.51（5.36-16.86）, respectively. Conclusion In Mongolian people, there have been clustering of risk factors in stage of prehypertension. Intervention measures among prehypertensives to prevent EH and other cardiovascular diseases are advised.

关 键 词：蒙古族 原发性高血压 高血压前期 危险因素 

分 类 号：R544.1[医药卫生—心血管疾病]