鼻咽癌放疗后放射性脑病患者医院内肺部感染临床分析  

Pulmonary Infection in Patients with Radiation Brain Injuries after Radiotherapy of Nasopharyngeal Cancer:A Clinical Analysis

作　　者：徐玲[1] 肖颂华[2] 刘军[2] 邢诒刚[2] 刘运林[1] 

机构地区：[1]泰安市中心医院ICU,山东泰安271000 [2]中山大学附属第二医院神经内科,广东广州510120

出　　处：《中华医院感染学杂志》2009年第5期519-520,531,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨鼻咽癌放疗后放射性脑病(RIB)医院内肺部感染的发生特点和原因以及寻找有效的治疗措施。方法对2004年10月-2007年6月RIB医院内肺部感染的病原菌培养结果、药敏试验结果进行回顾性调查并进一步分析。结果RIB并医院内肺部感染的发生率为68.85%,肺部感染发生主要与球麻痹、有创性操作、激素等药物的使用等有关;肺部感染病原菌以G-菌为主,占76.66%。结论RIB并医院内肺部感染与多种因素有关,根据药敏试验使用抗菌药物、加强对医院感染危险因素的控制是重要的防治措施。OBJECTIVE To study the characteristic of nosocomial pulmonary infection to find out the measures for prevention and control. METHODS The patients with radiation brain injuries （RIB） from Oct 2004 to Jun 2007 underwent retrospective investigation. The reasons and sites of pulinoary infection were analyzed. RESULTS The incidence of pulmonary infection of patients with RIB aider radiotherapy was 68.5%. Major factors of infection were bulb palsy, invasive treatment and hormone usage. The Gram-negative bacteria were the predominant pathogens. CONCLUSIONS The nosocomial pulmonary infection is related to many factors. Antibiotic usage according to drug susceptibility results and controlling of the risk factors are important measures to reduce the rate of infection.

关 键 词：放射性脑病 肺部感染 医院感染 

分 类 号：R181.32[医药卫生—流行病学]