红隼肺的组织结构及相关活性物质表达  

Histological structure and expression of inter related polypeptides in Aguila chrysaetos lung

作　　者：冯红丽[1] 俞诗源[1] 贾艳芳[1] 邓海平[1] 王昱[1] 牛宪峰[1] 

机构地区：[1]西北师范大学生命科学学院,甘肃兰州730070

出　　处：《西北师范大学学报（自然科学版）》2009年第1期101-106,共6页Journal of Northwest Normal University(Natural Science)

基　　金：国家自然科学基金资助项目(30370163);甘肃省自然科学基金资助项目(ZS031-A25-005-Z);甘肃省创新人才基金资助项目

摘　　要：红隼(Falcotinnunculus)属国家级保护动物,研究其器官组织及相关活性物质的表达,对于动物学和保护生物学研究都有重要意义.为了搞清红隼肺的组织结构特征,观察角质细胞生长因子(KGF)、c-Fos蛋白和Bax蛋白在肺中的表达情况,应用生物显微技术和免疫组织化学方法观察了2只红隼肺的组织结构,检测了KGF、c-Fos和Bax在肺中的表达.结果表明,红隼肺的表面覆盖有浆膜,肺实质由各级支气管及其周围的呼吸毛细管组成,肺房呈辐射状开口于三级支气管周围,呼吸毛细管相互吻合成网状,周围有丰富的毛细血管网.KGF、c-Fos和Bax在三级支气管的平滑肌细胞、肺房和呼吸毛细管的上皮细胞中呈免疫反应阳性.KGF、c-Fos和Bax可能发挥着不同的功能,它们的协同表达可能调控着鸟肺细胞的生长、发育及成熟.Histological structure of two Falco tinnunculus lung is obverved and expression of KGF, c-Fos and Bax is measured by light microscopy and immunohistochemical methods. Results show that the lung surface of Falco tinnunculu coveres with a serous, and the lung is consisted of bronchi and many breathing capillaries （minute trachea） around bronchi in nature. Pulmonary atrium radially disposes around tertiary bronchia. Many breathing capillaries anastomose reticulation with each other. There are rich pulmonary capillaries around minute trachea. KGF, c-Fos and Bax appear positive reaction, which are expressed in the smooth muscle cell of the tertiary bronchi and the epithelial cells of the pulmonary atrium and breathin capillaries. KGF, c-Fos and Bax may have different functions, their cooperative expression may control the growth, development and maturity of cells in birds lung.

关 键 词：红隼 肺 组织结构 免疫组织化学 KGF C-FOS蛋白 BAX蛋白 

分 类 号：Q954.4[生物学—动物学]