糖尿病患者检测β_2-微球蛋白的临床意义  

CLINICAL SIGNIFICANCE OF DETECTING β_2-MG IN BLOOD OF DIABETES MELLITUS PATIENTS

作　　者：胡春雷[1] 

机构地区：[1]大同市第三人民医院检验科,山西大同037008

出　　处：《承德医学院学报》2009年第1期21-23,共3页Journal of Chengde Medical University

摘　　要：目的:检测糖尿病(DM)患者的血β_2-微球蛋白含量,探讨其早期诊断DM肾功损害的意义。方法:将43例不同DM病程的患者按病程分为两组,分别检测两组患者的血β_2-微球蛋白含量和肾功能。结果:糖尿病肾病(DN)患者和DM患者的肾功能无明显区别,DN患者的β_2-微球蛋白含量明显高于DM患者(P<0. 05)。结论:β_2-微球蛋白检测可作为监测糖尿病病情、防治并发症的有效指标之一,对保护肾脏、减少糖尿病并发症有较高的临床价值。Objective：To detect the β2-MG content in blood of diabetes mellitus （DM） patients and investigate its significance for early diagnosis of DM kidney function impairment.Methods：43 DM patients with different course of disease were randomly divided into 2 groups according to course. The β2-MG content in blood and kidney function of patients were respectively detected.Results：There had no obvious difference about the kidney function between diabetic nephropathy （DN） patients and DM patients. The β2-MG content of DN patients was obviously higher than DM patients （P〈 0.05）.Conclusions： β2-MG can be acted as significant level to monitor pathogenetic condition of DM and prevent complications, and has high clinical value to decrease DM complications.

关 键 词：糖尿病 糖尿病肾病 Β2-微球蛋白 肾功能 

分 类 号：R587.1[医药卫生—内分泌]