糖尿病微血管病变与高血尿酸、高敏C反应蛋白的相关性研究  

Study of correlation between high serum uric acid,high sensitive C reactive protein and microangiopathy in patients with diabetes

作　　者：但刚[1] 胡宗海[1] 徐万清[1] 丁雁[2] 郭蔚[2] 古宇[1] 

机构地区：[1]成都军区总医院检验科,四川成都610083 [2]成都军区总医院市内门诊部,四川成都610083

出　　处：《西南国防医药》2009年第3期276-277,共2页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的:探讨高血尿酸、高敏C反应蛋白(hs-CRP)与糖尿病微血管病变的关系。方法:检测并比较23例无并发症糖尿病患者及25例并发微血管病变的患者血清中的尿酸、hs-CRP的水平。结果:糖尿病并发微血管病变者血清中尿酸、hs-CRP水平显著高于无并发症糖尿病患者(P<0.01),尿酸与hs-CRP水平呈正相关。结论:高水平的血尿酸和hs-CRP参与了糖尿病微血管病变的发生,并可能存在协同作用。Objective：To study the correlation between serum high uric acid （UA） ,high sensitive C reactive protein （hs - CRP） and microangiopathy in diabetic patients. Methods： UA and hs - CRP of 23 diabetic patients without complication and 25 diabetic patients with microangiopathy were detected, respectively. Results：The levels of UA and hs - CRP of diabetic patients with microangiopathy were higher than those of diabetic patients without complication （P 〈0.01 ）. There was a positive correlation between the level of UA and hs - CRP. Conclusion：The high level of serum UA and hs - CRP may participate in the development of diabetes microangiopathy and there is a synergistic effect between them on the process.

关 键 词：糖尿病 微血管病变 尿酸 高敏C反应蛋白 

分 类 号：R587.2[医药卫生—内分泌]