痰热清注射液合用倍能治疗肺部感染的临床研究  

Clinical Research of Tan Reqing Injection Combined with Meropenem to Treat Pulmonary Infection

作　　者：李晓利[1] 李彬[1] 刘宇[2] 张金花[1] 武若君[1] 陈昕[1] 孙沛[1] 

机构地区：[1]解放军总医院第二附属医院高干病房,北京100091 [2]解放军总医院第二附属医院呼吸科

出　　处：《临床肺科杂志》2009年第4期432-433,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的研究痰热清与广谱抗生素倍能合用能否减少肺部真菌感染发生率。方法采用病例对照研究的方法,调研2007年9月～2008年10月我院使用倍能与痰热清合用患者61例,采用病例与对照1∶1配比,通过追踪痰涂片真菌发生率。结果痰热清注射液合用倍能组真菌发生率与单用倍能组真菌发生率相比下降,优势比OR=5.71,OR的95%置信区间:2.75～11.88,P<0.001。结论痰热清与倍能合用,可以减少倍能的不良反应,使真菌发生率下降。Objective To investigate whether TanReqing Injection combined with broad-spectrum Meropenem can decrease incidence of fungal infection in lung. Methods Applying case control study method, the treatment group collecting from 07/2007 to 10/ 2008, was treated with TanReqing Injection and eropenem, while the control group with Meropenem alone. Two groups were matched by 1 ： 1, and fungal infection in lung was traced by sputum smear. Results Incidence of fungal infection of lung in treatment group decreased than in the control. The Odds ratio （OR） equals 5.71,95 % confidence interval of OR is 2. 75 to 11.88,P 〈 0. 001. Conclusion Meropenem combined with TanReqing Injection can make the fungal infect incidence of pulmonary infection decreased, and diminish the adverse effect of Meropenem.

关 键 词：痰热清 肺部感染 真菌 

分 类 号：R563.1[医药卫生—呼吸系统]