胜利油田住院肺结核病人耐药情况分析  

The analysis of drug resistance of pulmonary tuberculosis in Shengli oil field

作　　者：王桥霞[1] 

机构地区：[1]山东省胜利石油管理局结核病防治所,257055

出　　处：《临床肺科杂志》2009年第4期480-482,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的了解胜利油田2000～2008年住院肺结核病人对抗结核药物的耐药水平及耐多药情况。方法对2000年1月～2008年1月在我院住院痰培养阳性的结核病人进行4种抗结核药物(INH、RFP、EMB、SM)敏感性试验,统计并分析胜利油田肺结核患者耐药情况。结果共培养出784例结核杆菌菌株,耐药株为247例,总耐药率为31.5%,初始耐药率22.6%,获得性耐药率为57.9%,耐多药(MDR)率为9.6%。结论油田肺结核耐药率明显高于全国平均水平,因此合理化疗和贯彻全程督导治疗原则在结核病的控制方面十分关键。Objective To analyze during the years of 2000 - 2008 the patients drug resistance levels and multi-drug resistance rate in order to explore preventive and therapeutic method for pulmonary tuberculosis. Methods A retrospectively study was conducted on 784 cases with sputum cultural examination and 4 sensitivity testing of anti - tuberculosis drugs from Jan 2000 to Jan 2008. Results There were 133 cases with primary treatment and 114 cases with duplicate treatment in the patients of sputum cultural examination. Among them, the total drug resistance rate was 31.5%, the primary treatment patients of drug resistance rate was 22. 6% and duplicate treatment patients of drug resistance rate was 57.9%, and the multi-drug resistance was 3.3 %. Conclusion The drug resistance rate of anti-TB drug resistance with pulmonary tuberculosis was higher in the Shengli oilfield than the national average. Therefore it is key and important to have reasonable treatment and to provide Dos thesis in controlling pulmonary tuberculosis.

关 键 词：分枝杆菌 结核 抗药性 细菌 

分 类 号：R521[医药卫生—内科学] R378.16[医药卫生—临床医学]