纳米雄黄的粒度分析方法  

A method for granulometric analysis of realgar nanoparticles

作　　者：王晓波[1] 石焱[1] 袭荣刚[1] 姚文[1] 隋淼[1] 杨晓波[1] 

机构地区：[1]中国人民解放军第210医院药剂科,大连116021

出　　处：《药学服务与研究》2009年第1期52-54,共3页Pharmaceutical Care and Research

摘　　要：目的:建立纳米雄黄的粒度分析方法。方法:利用原子力显微镜对纳米雄黄的表观形貌进行直接观察测定,用激光光散射法对纳米雄黄的粒度分布范围进行分析测定。结果:首次得到原子力显微镜下纳米雄黄形貌特征图;激光光散射颗粒度测定仪的测量显示,粒径在30nm以下的纳米雄黄约90%。结论:本研究所采用的原子力显微镜法和激光光散射法快速、简便、准确,可用于纳米雄黄的粒度检测。Objective： To establish a method for granulometric analysis oi realgar nanoparnctes, wletnoQs： i ne morphology of realgar nanoparticles was observed by atomic force microscopy and their diameter distribution was determined by laser scat tering particle size distribution analyzer. Results： About 90% of realgar nanoparticles whose diameter was under 30 nm were obtained. The limpid graph of realgar nanoparticles under atomic force microscopy was obtained for the first time. Conclusion： The methods used in this study are rapid, simple and accurate for granulometric determination of realgar nanopartieles.

关 键 词：纳米粒子 雄黄 显微镜检查.原子力 激光光散射 粒子大小 

分 类 号：R917.4[医药卫生—药物分析学] R943.41[医药卫生—药学]