B淋巴细胞吞噬功能研究进展  

Progression in the study on the phagocytosis function of B lymphocyte

作　　者：高杨[1] 高继鑫[1] 刘玉峰[1] 

机构地区：[1]第四军医大学西京医院皮肤科,西安710032

出　　处：《国际免疫学杂志》2009年第2期157-160,共4页International Journal of Immunology

摘　　要：以往的观点认为只有巨噬细胞、单核细胞、粒细胞和树突状细胞是专职的吞噬细胞，而B细胞作为免疫系统的抗体产生细胞，虽然能够产生特异的免疫球蛋白与抗原结合，却不具备吞噬能力。但最近的研究指出硬骨鱼类（彩虹鳟鱼）和两栖类（爪蟾）的B细胞可以吞噬颗粒抗原，首次揭示了进化上较为原始的B细胞同样具有吞噬能力。众多研究提示哺乳动物B-1 B细胞很可能具有吞噬能力。It was accepted in the past that only these cells such as macrophage, histoleucocyte, granular cell and dendritic cell are phagocytes, while B lymphocyte has no ability to phagocytize, although it can generate specific immune globulin for antigen binding. However recent studies indicate that B lymphocyte of osteichthyes （trout） and amphibia （xenopus laevis） can phagocytize particulate antigen, these studies for the first time revealed that relatively archaic B lymphocyte has ability to phagocytize too. Numerous studies reveal that B-1 cell in mammalian probably has ability to phagocytize.

关 键 词：B淋巴细胞 吞噬 进展 

分 类 号：R329[医药卫生—人体解剖和组织胚胎学]