科莫非配合促红素治疗慢性肾功能不全贫血临床研究  

Analysis of effect in treating anemia of Chronic Renal failure with Cosmofer accompanied with Epo

作　　者：刘永军 潘健涛[2] 张伟君 

机构地区：[1]佛山市禅城区中心医院,广东佛山528031 [2]广州中山大学附属第一医院肾内科,广东广州510080

出　　处：《佛山科学技术学院学报（自然科学版）》2009年第1期83-85,共3页Journal of Foshan University(Natural Science Edition)

摘　　要：目的探讨科莫非配合促红细胞生成素(Epo)治疗慢性肾功能不全(CRF)患者贫血的疗效。方法选择CRF行血液透析(HD)并用Epo治疗贫血患者30例,其中15例选用静脉注射科莫非(cosmofer)治疗,15例选用口服力蜚能治疗,观察2个月。结果用Epo后,2组患者贫血均改善,力蜚能组Hb每月上升14.9 g.L,Epo用量比得莫非组多15.4%;而科莫非组可迅速改善CRF透析患者红细胞生成状态,Hb每月上升23.7 g.L,Epo用量较小,与力蜚能组比较差异有显著性(P<0.01)。结论静性注射科莫非可作为HD患者长期补铁方式,配合Epo治疗,疗效确切。Objective To investigate the effect of treatment in anemia of CRF by Cosmofer accompanied with Epo. Methods 30 anemia patients with CRF were treated with hemodialysis and Epo, 15 of them used Cosmofer in venion, 15 of them used oral Niferex. All patients were followed for two months. Results All patients＇ anemia were improved; the value of hemoglo-bulin in Cosmofer group increased 23.7g per month, and was higher than that of Niferex （14.9 g/month）（P〉0.01）. The dose of Epo in Cosmofer group was lower than the oral Niferex group. Conclusion The cosmofer in venion accompanied with Epo ,nay be effective in treating anemia in CRF, and Cosmofer in venion can be regarded as a long-method to supply ferror for CRF.

关 键 词：科莫非 促红细胞生成素 贫血 肾功能不全 慢性 

分 类 号：R692[医药卫生—泌尿科学] R556[医药卫生—外科学]