胎儿终丝形态学及光镜研究  

Study on the morphology and ultrastructure of fetus ilium terminale

作　　者：张春雷[1] 刘福云[1] 夏冰[1] 陈明伟[1] 季泽娟[1] 

机构地区：[1]郑州大学医学院三附院小儿骨科,郑州450052

出　　处：《国际外科学杂志》2009年第3期179-181,F0003,共4页International Journal of Surgery

基　　金：河南省科技厅重点攻关项目（No.001170648）

摘　　要：目的观察正常胎儿终丝形态及其结构，为研究脊髓栓系综合征患儿的终丝结构提供参照标准。方法测量并切除10例新鲜流产胎儿终丝，取其纵、横切面行光镜观察。结果终丝由1～5μm直径的弹簧样纵向胶原纤维束组成，纤维束呈层分布，每层之间有空隙；层内纤维束之间也有空隙。层间隙、束间隙及束内每根纤维间由横向精细网状纤维连结，也可见到胶原纤维束交叉连结各束间及层间纤维。弹性纤维分散在胶原纤维束内或集中排列在胶原纤维束间。间隙可见少量毛细血管。结论终丝的结构及成分改变可能与脊髓栓系综合征的发病密切相关。Objective The ilium terminale （FT） plays an important role in the pathophysiology of tethered cord syndrome （TCS）. The study on morphology and structure of fetus FT can provide reference standard for diagnosis of TCS . Methods Ten fresh human aborted fetuses had their illa measured and removed. Transversal and longitudinal sections of the middle, and distal thirds of FT were submitted to light microscopy analysis with four different techniques. Results The bulk of the FT is composed of 1 - 5μm thick spring like longitudinal bundles of colla- gen separated by 5 - 30 μm layer intervals and 1 - 5 μm intervals in the layer, although a small quantity of capillaries and other elements may be present. Collagen bundles can also be found between layers and bundles. Abundant longitudinally oriented elastic fibers are found inside or between collagen bundles. Conclusion A complex tridimensional structure composed by ordered arrangement of spring like fibers and small quantity of capillaries should elicit considerable elastic properties to the FT. Tts alternation of structure and element maybe involved in TCS closely.

关 键 词：终丝 脊髓栓系综合征 组织解剖学 纤维 

分 类 号：R714[医药卫生—妇产科学]