鲍曼不动杆菌临床感染分布及耐药性分析  

Analysis of Distribution and Drug Resistance of Infections of Acinetobacter Baumannii

作　　者：王新华[1] 易凯[1] 李龙平[1] 

机构地区：[1]中南大学湘雅医学院益阳临床学院,湖南益阳413000

出　　处：《中国现代医生》2009年第6期13-14,16,共3页China Modern Doctor

摘　　要：目的了解鲍曼不动杆菌的感染分布及耐药性状,为临床治疗提供依据。方法回顾性统计分析104株鲍曼不动杆菌的标本来源、感染科室分布及耐药性状。结果104株鲍曼不动杆菌中96.2%(100/104)分离自住院患者,3.8%(4/104)分离自门诊患者;痰标本分离率最高(74%);主要引起神经外科(36.5%)和儿科(12.5%)患者的呼吸道感染;该菌对庆大霉素高度耐药(70.2%),对美洛培南高度敏感(97.1%)。结论鲍曼不动杆菌是医院感染重要的条件致病菌,其对抗生素普遍耐药,只对碳青霉烯类抗生素敏感。临床应合理使用抗生素,减少多重耐药菌株的产生。Objective To study the distribution and drug resistance of Acinetobacter baumannii,and offer reasonable experimental data for clinical therapeutics. Methods A total of 104 Acinetobacter baumannii isolates were retrospectively analyzed according to specimen source,infection in different departments and drug-resistance. Results A total strains of 104 Acinetobacter baumannii were isolated,96.2% of them isolated from inpatients,and 3.8% of them isolated from outpatients. The isolation rate of Acinetobacter baumannii was 74.0% in sputum specimens and the majority of the isolates caused respiratory tract infection in neurosurgery（36.5%）and pediatrics（ 12.5% ） department inpatients. The rate of resistance to Gentamicin was the highest（70.2% ）. 97.1% of them were susceptible to meropenem. Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in hospital infection which shows high rate of resistance to routine antimicrobial agents. The isolates of Acinetobacter baumannii were susceptible to carbapenems. Antimicrobial agents should be used rationally to decrease multi-drug resistance.

关 键 词：鲍曼不动杆菌 感染 耐药 条件致病菌 

分 类 号：R515[医药卫生—内科学]