猪组织和血浆中磺胺二甲嘧啶残留分布规律的数学模型分析  

Analysis of mathematical model for distribution regularity of sulfamethazinum residues in porcine tissues and plasma

作　　者：杨秀娟[1] 高士争[1] 葛长荣[1] 陶琳丽[1] 张锦红[1] 张曦[1] 

机构地区：[1]云南农业大学云南省动物营养与饲料重点实验室,云南昆明650201

出　　处：《中国兽医学报》2009年第3期318-322,共5页Chinese Journal of Veterinary Science

基　　金：国家科技支撑计划资助项目(2006BAD14B03-6)

摘　　要：采用高效液相色谱法检测猪肌肉、肾脏、肝脏和血浆中的磺胺二甲嘧啶残留量,通过对饲料中磺胺二甲嘧啶添加量和组织、血浆中残留量回归关系不同数学模型的分析,确立残留分布的规律的最佳数学模型。饲料中SM2的添加量在100～300μg/g的范围内,饲料添加量与猪组织(肌肉、肾脏、肝脏)、血浆的残留数学模型分别为:y=0.241 6e0.006 1x;y=1.9691e0.002 5x;y=3.049 5e0.001 9x;y=4.386 2e0.003 7x。通过对猪活体血浆样品的检测,根据建立的最佳残留数学模型,可算出饲料中磺胺二甲嘧啶的添加量和肌肉、肾脏、肝脏中磺胺二甲嘧啶的残留量,实现活体的监测。The sulfamethazinum residues amounts were detected using the method of high liquid chromatography analysis from porcine muscle,liver,kidney and plasma. By analysis of different mathematical model between different added levels in feed and residues in tissues and plasma, the best mathematical model of distribution regularity was choiced for analysis sulfamethazinum residues amount in tissues and plasma. From 100 μg/g to 300 μg/g feed added level,linear regression between feed added and muscle,kidney,liver residues of SM2 is y = 0. 241 6e^0.0061x, y = 1. 969 1e^0.0025x ,y = 3. 049 5e^0.0019x ,y = 4. 386 2e^0.0037x respectively. By analysis residues amount in plasma,accord- ing to the mathematical model,may figure out feed added and residues amount in the muscle, the kidney, the liver, which can realizes the living specimen monitor.

关 键 词：磺胺二甲嘧啶 残留 数学模型 猪 

分 类 号：S859.79[农业科学—临床兽医学]