一些含噻唑杂环的萘酰亚胺衍生物的合成  

Synthesis and characterization of some derivatives of 1,8-naphthalimides containing thiazole heterocyclics

作　　者：覃雯[1,2] 徐健飞[1] 刘茜[3] 张业[1,2] 

机构地区：[1]桂林师范高等专科学校化学与工程技术系,广西桂林541001 [2]广西师范大学化学化工学院,广西桂林541004 [3]梧州学院教师教育系,广西梧州543002

出　　处：《化学试剂》2009年第3期200-202,共3页Chemical Reagents

基　　金：国家自然科学基金资助项目(20362002,2076-2001)

摘　　要：以6-溴-1H,3H-苯并[de]吡喃-1,3-二酮为起始原料,通过硝化、氢化还原、关环和亚酰化反应,合成了3个含噻唑杂环的萘酰亚胺衍生物:N-丙基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮、N-丁基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮和N-羟乙基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮。产物经过IR1、HNMR和元素分析进行了表征。Starting from 6-bromo-1H,3H-benzoisochromene-1,3-dione,three new compounds——N-propyl-9-phenyl-benzo-[de]-thiazole-[4,5-g]-isoquinoline-4,6-dione,N-butyl-9-phenyl-benzothiazole-[4,5-g]-isoquinoline-4,6-dione and N-hydroxyethyl-9-phenyl-benzothiazole-[4,5-g]-isoquinoline-4,6-dione were synthesized through the reactions of nitration,hydrogenation,cyclization and imidation.The compounds were characterized by IR,1HNMR and elemental analyses.

关 键 词：合成 萘酰亚胺 噻唑 杂环 表征 

分 类 号：O626[理学—有机化学]