N-氨基哌啶盐酸盐的合成  

Preparation of N-amino piperidine hydrochloride

作　　者：冯润良[1] 宋智梅[1] 

机构地区：[1]济南大学化学化工学院,山东济南250022

出　　处：《化学试剂》2009年第3期223-224,共2页Chemical Reagents

基　　金：济南大学博士启动基金资助项目(B0511)

摘　　要：以哌啶为起始原料,经N-亚硝化、还原以及成盐等合成操作制备标题化合物,总收率66.5%。该合成路线操作简单、收率高,所选试剂价格适中,适合进行工业化生产。The title compound was obtained from N-nitrosoamination of piperidine and reduction of nitroso group followed by salt-forming of hydrochloride.N-amino piperidine was obtained at 66.5% yield.The results showed that the synthetic process was simple with high product yield.The synthetic route,which required inexpensive raw materials,was suitable for manufacture in commercial scale.

关 键 词：N-氨基哌啶盐酸盐 合成 利莫那班 

分 类 号：O624.6[理学—有机化学]