全身炎症反应综合征患儿核因子-kB活化及IL-6合成的检测  

A Study of the Activation of NF-kB and Synthesise of IL-6 in Systemic Inflammatory Response Ssyndrome

作　　者：袁柳芬[1] 陈敬国[2] 陈小燕 

机构地区：[1]南方医科大学附属小榄医院儿科,广东中山528415 [2]中山大学附属中山医院新生儿科,广东中山528403 [3]广州增城市人民医院儿科,广东增城511300

出　　处：《临床医学工程》2009年第3期81-82,共2页Clinical Medicine & Engineering

基　　金：广州市科技计划项目(编号:2006-yb-199)。

摘　　要：目的探讨全身炎症反应综合征核因子-kB活化及IL-6合成的情况。方法用中性粒细胞核因子-kB活性测定法、血清免疫因子IL-6放射免疫浓度测定法测定30例全身炎症反应综合征患儿及30例正常人组中性粒细胞核因子-kB活性、血清免疫因子IL-6放射免疫浓度。结果全身炎症反应综合征患儿核因子-kB活化及IL-6合成增加。结论患儿发生全身炎症反应综合征时存在核因子-kB活性及IL-6合成的变化。Objective To explore the activation of NF-κB and synthesise of IL-6 in systemic inflammatory response syndrome. Methods Children were divided into experiment group and normal group. The changes of the activation of NF-κB and synthesise of IL-6 were observed by using especting NF-κB in PMN and radioimmunoassay. Results The activation of NF-κB and synthesise of IL-6 increased obviously in systemic inflammatory response syndrome. Conclusion The changes of the activation of NF-κB and synthesise of IL-6 were in systemic inflammatory response syndrome.

关 键 词：全身炎症反应综合征 核因子-KB 白细胞介素6 

分 类 号：R473.72[医药卫生—护理学]