新型壳聚糖季铵盐衍生物的合成与表征  

Synthesis and Characterization of a Novel Quaternary Chitosan Derivative

作　　者：胡章[1] 李思东[1] 李先文[1] 欧春艳[1] 侯婷婷[1] 

机构地区：[1]广东海洋大学理学院,广东湛江524088

出　　处：《广东海洋大学学报》2009年第1期58-61,共4页Journal of Guangdong Ocean University

基　　金：广东海洋大学自然科学基金(0612172)

摘　　要：采用甲磺酸作为溶剂兼作氨基保护试剂,对壳聚糖上的羟基选择性酯化,再游离出氨基并对其氯乙酰化,最后进行吡啶成盐,得到新型水溶性的壳聚糖季铵盐衍生物,产物的结构通过核磁共振氢谱和红外光谱进行了表征,从而为壳聚糖季铵盐衍生物的制备提供了一种新途径。A novel quaternary chitosan derivative was prepared by selective esterification of hydroxyl groups of chitosan by using methane sulfonic acid as solvent and protection reagent of amino group, followed by liberating amino group and chloroacylation, and finally quatemization with pyridine. While the chitosan derivative structures were characterized with 1H NMR and FT-IR, a novel approach to quaternary chitosan derivatives was provided.

关 键 词：壳聚糖 季铵盐 合成 表征 

分 类 号：S968.252[农业科学—水产养殖]