北京地区36家医院2005-2007年抗抑郁药利用分析  

Utilization of Antidepressant Drugs in 36 Hospitals in Beijing Area from 2005 to 2007

作　　者：吴润伟[1] 郭海飞[2] 郝红兵[1] 

机构地区：[1]首都医科大学附属北京安定医院药剂科,北京市100088 [2]北京大学第六医院药剂科,北京市100191

出　　处：《中国药房》2009年第8期572-574,共3页China Pharmacy

摘　　要：目的:了解北京地区抗抑郁药的应用情况及趋势。方法:采用世界卫生组织推荐的限定日剂量方法,对北京地区36家医院2005～2007年抗抑郁药的应用情况进行统计、分析。结果:该地区抗抑郁药销售金额、用药频度均逐年大幅增长,选择性5-羟色胺再摄取抑制剂(SSRIs)占抗抑郁药总销售金额的88%以上,氟西汀、帕罗西汀、西酞普兰占销售金额、用药人数的前3位,传统的三环类、四环类药市场份额有所减少,但仍有稳定的用药人群。由于抑郁症患者增加,呈现出用药需求的多样性。结论:氟西汀等SSRIs一直占据北京地区抗抑郁药市场的主导地位。我国应加大力度,尽早研发出具有自主知识产权的抗抑郁药。OBJECTIVE： To investigate the clinical utilization and the tendency of antidepressant drugs in Beijing area. METHODS： Using the analytical method of the defined daily dose （DDD） recommended by WHO, the application of antidepressant drugs in Beijing from 2005 to 2007 was analyzed statistically. RESULTS： The consumptive sum and DDDs of antidepressants increased significantly year by year, with SSRIs representing more than 88% of all the antidepressant drugs in terms of the consumptive sum, leading the first 3 places in terms of consumption sum and DDDs were fluoxetine, paroxetine and citalopram. The market share of traditional tricyclics and tetracyclines showed a slight reduction, but there were still a stable population of these drugs. CONCLUSION： SSRIs such as fluoxetine have been dominated the antidepressants market in Beijing area.

关 键 词：抗抑郁药 北京地区 5-羟色胺再摄取抑制剂 应用分析 

分 类 号：R969.3[医药卫生—药理学] R971.6[医药卫生—药学]