影响帕金森病患者选择治疗方法的因素调查与分析  

Analysis of the Factors Influencing the Treatment of Parkinson Disease

作　　者：张大伟[1] 吴惠金[2] 马丽颖[3] 张卓伯[3] 

机构地区：[1]佳木斯大学第一附属医院药剂科,佳木斯市154002 [2]牡丹江医学院第二附属医院药剂科,牡丹江市157009 [3]哈尔滨医科大学第四临床医院,哈尔滨市150001

出　　处：《中国药房》2009年第8期638-640,共3页China Pharmacy

摘　　要：目的:了解帕金森病的药物治疗情况,分析影响患者选择治疗方法的因素。方法:共调查269例患者,按采用的不同治疗方法分为多巴胺受体激动药或安坦治疗组(Ⅰ类治疗)、左旋多巴治疗组(Ⅱ类治疗)、左旋多巴+多巴胺受体激动药治疗组(Ⅲ类治疗)。对患者年龄、性别、病情、受教育程度、职业、收入等因素进行统计、分析。结果与结论:在选择不同治疗方法的患者中,年龄、性别、病情、受教育程度、职业、收入的似然比检验P<0.05。经Logistic多元回归分析表明,年龄、性别、病情、受教育程度、职业、收入对治疗方法的选择有影响。OBJECTIVE： To investigate the pharmacotherapy for Parkinson disease （PD） and the factors influencing the choice of the treatment schemes for the PD patients. METHDOS： A total 269 patients with PD were assigned to 3 groups： Group Ⅰ （Dopamine Agonist or Antan）, Group Ⅱ （L- dopa）, and Group Ⅲ （L- dopa plus Dopamine Agonist）. The possible relative factors such as patients＇ age and sex, pathogenetic condition, educational level, occupation and income etc were analyzed statistically. RESULTS： The P value of the likelihood ratio test concerning the investigated factors such as age, sex, pathogenetic condition, education level, occupation and income were all less than 0.05 among patients treated with different kinds of therapy. The logistic regression analysis showed that all the six factors mentioned above had influence on the choice of therapy. CONCLUSION： The PD patient＇s selection of therapy was affected by his age and sex, pathogenetic condition, education level, occupation and income.

关 键 词：帕金森病 治疗 Logistic多元回归 

分 类 号：R952[医药卫生—药学] R969.3