急性毒鼠强中毒血清心肌酶学及心肌钙蛋白T检测的临床意义  

Clinical Significance of Detecting Serum Cardiac Enzymes and cTnT with Acute Tetarmine Poisoning

作　　者：王翔[1] 周平[1] 王建东[1] 

机构地区：[1]四川省人民医院急救中心,成都市610072

出　　处：《医药论坛杂志》2009年第3期1-2,共2页Journal of Medical Forum

摘　　要：目的探讨急性毒鼠强中毒时血清心肌酶及心肌钙蛋白T的变化。方法测定40例急性毒鼠强中毒患者血清心肌酶学天冬氨酸转移酶(AST)、肌酸磷酸激酶(CK)、乳酸脱氢酶(LDH)、α-羟丁酸脱氢酶(α-HBDH)、肌酸激酶同功酶(CK-MB)及心肌钙蛋白T,同时以健康人及急性心肌梗死作为对照。结果急性毒鼠强中毒HP患者血清心肌酶明显高于健康者(P<0.05),而心肌钙蛋白T阳性率明显低于心梗组(P<0.01)。结论急性毒鼠强中毒时血清心肌酶升高主要为骨骼肌损伤与脑组织缺氧及心肌损伤也有关,但不能作为心肌损伤的唯一判断标准。Objective To explore the changes and clinical significance of serum cardiac enzymes and cTnT in patients with tetarmine poisoning. Methods Levels of serum cardiac enzymes aminotransferase （ AST）, creatine kinase （CK）, lactic dehydrogenase （ LDH ）, α- hydroxybutyrate dehydrogenase （ α- HBDH）, CK isoenzyme and cTnT were measured in 40 patients with acute tetarmine poisoning. They were compared to that of health group and AMI group. Results The levels of serum myocardial enzyme in patients with acute tetarmine poisoning were singnificantly higher than that of health group （P 〈 0. 05） , But positive rate was singnificantly lower than that of AMI group （P 〈 0. 01 ） . Conclusion The rise of serum myocardial enzymes was related to convulsion of skeletal muscle, hypoxic brain and the myocardial injury. Its wasn＇ t only standard for accessing myocardial injury.

关 键 词：急性毒鼠强中毒 血清心肌酶 心肌钙蛋白T 

分 类 号：R595.4[医药卫生—内科学]