吡喹酮隔年普治控制血吸虫病效果研究  

SCHISTOSOMIASIS CONTROL EFFECT BY PRAZIQUANTEL MASS TREATMENT ONCE EVERY 2 YEARS

作　　者：尹治成[1] 吴子松[1] 钱晓洪[1] 来建[1] 戴晓斌[1] 张桂盛[1] 张奕[1] 金介梅 李兴加[2] 赵联国 尹洪智[2] 李昌德 

机构地区：[1]四川省寄生虫病防治研究所,成都610041 [2]西昌市血吸虫病防治站,西昌615000

出　　处：《实用寄生虫病杂志》1998年第1期11-15,共5页Journal of Practical Parasitic Diseases

基　　金：世界银行贷款中国血吸虫病控制项目!JRMC

摘　　要：1994—1997年在感染率＞15％的流行村进行为期4年的吡喹酮隔年普治（A组）和每年普治（B组）对照试验显示，A组人群感染率下降78．23％，耕牛感染率下降63．61％，人群EPG下降79．90％；B组分别下降77．69％、46．40％和92．84％。两组粪检阳性者的B型超声波图像干预前后无显著性差异。两组效果相当，但是A组费用仅为B组的1／2。对于经济欠发达的高度流行区，用吡喹酮隔年普治1次是一种既能有效控制血吸虫病，又能低成本长期运作的防治手段。Frm 1994 to 1997， a study on schistosomiasis control effect by different praziquantel mass treatment in tervals i．e．once every 2 years（Group A） and once every year（Group B） was conducted in hyper－endemic villages (human infection rate>15%) in Xichang City， Sichuan．The results showed that in Group A and B，the human infection decreased by 78． 23% and 77. 69%， the cattle Infection rate decreased by 63.61％And 46.40%,adEPG in popuhoin decreasedby79.90%and92.84%respetively.Besides,therewere no significant differences between Group A and B in ultrasonographic examinatlon before and after intervention．It has been suggested by the authors that in undeveloped hyper-endemic areas， praziquantel mass treatment once every 2 years may be accepted as a practical measures in schistosomiasis control programe．

关 键 词：血吸虫病 全民化疗 吡喹酮 流行病学 

分 类 号：R532.210.1[医药卫生—内科学]