应用鲎试剂法检测盐酸左氧氟沙星注射液热原  

Studies on the Feasibility of Applying TAL Test Method on the Pyrogen Test of Levofloxacin Injection

作　　者：郑赛利[1] 

机构地区：[1]中山大学生命科学学院,广州510275

出　　处：《中山大学研究生学刊（自然科学与医学版）》2008年第4期54-60,共7页Journal of the Graduates Sun YAT-SEN University(Natural Sciences.Medicine)

摘　　要：分别采用鲎试剂检查法及家兔升温度法对盐酸左氧氟沙星注射液中的热源进行检测。结果鲎试剂法检查盐酸左氧氟沙星注射液热源合格,家兔升温度法检查盐酸左氧氟沙星注射液热源合格。两种方法比较得出应用鲎试剂法检查盐酸左氧氟沙星注射液热源操作简单易行,试验费用低,结果迅速可靠,灵敏度高,可用于该制剂的质量控制。The pyrogen in the Levofloxacin Injection was tested by TAL test method and Rabbits method. The results from the TAL test method were qualified and the results from Rabbits method were qualified. Compared with Rabbits method, TAL test method is more sensitive and convenient. It can be used for the quality control of the Pyrogen test of Levofloxacin Injection.

关 键 词：盐酸左氧氟沙星 热源检查 鲎试剂法 升温度法 

分 类 号：TQ460.7[化学工程—制药化工] S859.796[农业科学—临床兽医学]