三七总皂甙预防兔创伤性肢体深静脉血栓形成的实验研究  

Experimental Study of Radix Notoginseng Total Saponins in preventing Traumatic Deep Venous Thrombosis

作　　者：黄有荣[1] 蒋攀峰 

机构地区：[1]广西中医学院附属瑞康医院,南宁530011 [2]河南省新乡市人民医院

出　　处：《中国中医骨伤科杂志》2009年第3期15-17,共3页Chinese Journal of Traditional Medical Traumatology & Orthopedics

摘　　要：目的:探讨静脉注射三七总皂甙对兔创伤性深静脉血栓形成的影响。方法:按随机原则分为三七总皂甙预防组、低分子肝素钠预防组、动物模型对照组,每组10只兔。两预防组于造模后第2天每天给药,持续8d。作相关血液流变学指标检测及记录各组血栓形成情况,并作统计学分析。结果:三七总皂甙及低分子肝素钠皆有较好的降低血液粘度及改善血液"高凝状态"的作用。结论:三七总皂甙与低分子肝素钠同样具有减少创伤性下肢深静脉血栓形成的作用。Objective： To study the influence of radix notoginseng total saponins （RNTS） injection on lower--extremity traumatic deep venous thrombosis （TDVT）. Methods： Thirty rabbits were randomly divided into 3 groups （n= 10 each）： RNTS preventive group, low--molecular--weight heparin sodium （LHS） preventive group and model group. Two days after TDVT modeling, the 2 preventive groups were given RNTS and LHS injection respectively for 8 days. The related haemorheology indexes were measured and statistically analyzed. Results： Both preventive groups obviously decreased blood viscosity and improved blood hypercoagulable state. Conclusion： RNTS has the same preventive effect on TDVT as LHS does.

关 键 词：下肢深静脉 血栓 三七总皂甙 低分子肝素钠 动物实验 

分 类 号：Q954.563[生物学—动物学]