清脑醒神贴基质的研究  

Study on Matrix of Qingnaoxingshen Patch

作　　者：王锐[1] 吕邵娃[1] 管庆霞[1] 李永吉[1] 

机构地区：[1]黑龙江中医药大学药学院,哈尔滨150040

出　　处：《黑龙江医药》2009年第2期139-140,共2页Heilongjiang Medicine journal

基　　金：黑龙江中医药大学校基金项目资助

摘　　要：目的:设计研究一种粘性较高、可反复揭贴、厚度轻薄、无色透明的可用于穴位给药的亲水性贴片基质。方法:采用正交试验法考察贴片基质的配方组成。结果:制备出一种粘性适中、剥离性好、可重复揭贴的新型水溶性贴片空白基质。结论:此基质各项指标均符合外用贴敷要求。其成功的开发研制为继续开展经皮传递系统的研究奠定了基础。Objective： To optimize the matrix of Qingnaoxingshen patch. The matrix has high glutinosity, thinness, transparency, and can be used repeatedly. Methods：orthogonal design was used for studying content of matrix. Result：The optimized formula of matrix has good adhesion overlay performance and can be used repeatedly. Conclusion：It is useful for exterior application. The study laid a good Foundation for TDDS development.

关 键 词：清脑醒神贴 基质 经皮传递系统 

分 类 号：TQ460.6[化学工程—制药化工]