IL-10在小儿支原体肺炎发病机制中的作用  

The Efects of IL-10 on Mycoplasma Pneumonia in Children

作　　者：潘黎明[1] 王跃[2] 张海英[3] 

机构地区：[1]吉林大学第一医院,吉林长春130021 [2]吉林大学中日联谊医院,吉林长春130021 [3]吉林大学公共卫生学院,吉林长春130021

出　　处：《中国实验诊断学》2009年第3期376-378,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的研究IL-10在小儿支原体肺炎(Mycoplasma pneumoniae pneumonia,MPP)发病机制中的作用,为MPP的诊断治疗提供实验依据。方法通过双抗体夹心ELISA法检测MPP患儿血清IL-10水平。结果肺炎支原体肺炎MPP组血清IL-10水平明显低于健康对照组,且恢复期仍处于低水平状态。结论IL-10在MPP的发病机制中起一定作用,可能参与了MPP的原发肺部损伤和肺外并发症的形成。Objective To approach the effect of these three cytokines ahove-mentioned in MPP, and reveal the immunolngical pathogenesis of MPP.Methods we compared the blood serum level of IL-10 in four groups below using ELISA method.Results The results showed, compared with the healthy children, the blood serum level of IL- 10 changed significantly in children of MPP. Conclusion IL-10 play a part in the pathogenesis of MPP,it probably participate in the primary damage in lung, and complications extrapulmonary.

关 键 词：IL-10 小儿支原体肺炎 

分 类 号：R725.6[医药卫生—儿科]