步长稳心颗粒与胺碘酮联合治疗老年室性早搏  

Clinical Observation of the Treatment of Premature Ventricular Contraction in Senior Patients with Combination Therapy of Bu Chang Wen Xin Granule and Amiodarone

作　　者：丁军[1] 崔卫华[1] 黄通瑞[1] 田秀恩[1] 李征[1] 王明玉[1] 

机构地区：[1]解放军白求恩国际和平医院,石家庄050082

出　　处：《临床误诊误治》2009年第3期19-20,共2页Clinical Misdiagnosis & Mistherapy

摘　　要：目的：观察步长稳心颗粒与胺碘酮联合治疗老年室性早搏的效果。方法：将2004年2月～2007年4月门诊及住院治疗的64例老年室性早搏随机分为两组。治疗组给予步长稳心颗粒9g每日3次口服，胺碘酮0．2g每日3次口服，7天后胺碘酮减为每日2次，维持量为每日0．1-0．2g。对照组单纯予胺碘酮口服，用法同治疗组。分别观察两组治疗前后主观症状、心电图、24小时动态心电图、血尿常规、血糖、血脂、肝肾功能等变化。结果：治疗组总有效率为82．34％，对照组为66．66％，两组比较差异有统计学意义（P〈0．05）。结论：步长稳心颗粒与胺碘酮合用治疗老年室性心律失常疗效满意，不良反应轻微，值得临床推广应用。Objective：To observe the effect of Bu Chang Wen Xin Granule combined with Amiodarone on premature ventricular contraction （PVC）. Methods ：64 old patients with PVC from February 2004 to April 2007 in our hospital were randomly divided into two groups. The treatment group was given 9 g of Bu Chang Wen Xin Granule tid and 0.2 g of Amiodarone tid. The dosage was reduced to bid and maintained at 0.1-0.2 g per day. The control group was only given Amiodarone with the same dosage as in the treatment group. Subjective symptoms, electrocardiogram ,24-hour electrocardiogram, blood routine, urine routine, glucose, lipid, liver function,scrume creatinine,blood urea nitrogen,blood uric acid were monitored in both the groups before and after treatment. Results： The effective rates in the treatment group and control group were 82.34% and 66.66% respectively with a difference of statistical significance （P 〈 0. 05 ）. Conclusion：The combination therapy of Bu Chang Wen Xin Granule and Amiodarone has shown remarkable therapeutic efficacy in treating old-aged patients with premature vcntricular contraction with little side effect. It is of clinical value.

关 键 词：室性早搏复合征 胺碘酮 步长稳心颗粒 药物疗法 联合 

分 类 号：R541.7[医药卫生—心血管疾病]