江苏省农村散发性戊型肝炎流行病学特征分析  

Analysis on the epidemiological characteristics of the sporadic cases with hepatitis E infection in the rural area in Jiangsu province

作　　者：艾星[1] 张雪峰[2] 黄守杰[3] 姜汉民[4] 王一军[4] 杨昌林[4] 蔡加平[4] 王忠泽[4] 闫强[3] 苗季[3] 张军[3] 朱凤才[2] 

机构地区：[1]东南大学公共卫生学院,南京210009 [2]江苏省疾病预防控制中心,南京210009 [3]厦门大学国家传染病诊断试剂与疫苗工程技术研究中心 [4]东台市疾病预防控制中心

出　　处：《中国人兽共患病学报》2009年第3期253-256,共4页Chinese Journal of Zoonoses

基　　金：国家高技术研究发展计划(863计划)(2006AA02A209)资助

摘　　要：目的了解江苏省农村散发性戊型肝炎的流行病学特征。方法通过建立覆盖市、镇、村三级医疗卫生服务机构的疑似肝炎主动监测网络,系统全面地监测戊型肝炎病例的发病情况。结果主动监测网络的敏感性明显高于网络报告系统,能更加准确、全面地掌握戊肝的发病规律。结果显示戊型肝炎病例占疑似急性肝炎病例的26.7%,男性戊肝发病率高于女性(P<0.01);发病随着年龄增长而上升,多见35岁以上人群;全年均有发病,冬春季节较高;戊型肝炎病毒株HEV1、4型并存,但以HEV4型为主(92.5%)。结论疑似肝炎主动监测系统数据显示目前戊肝发病率有被低估的风险。To understand the epidemiological characteristics of the sporadic cases with hepatitis E infection in the rural area of Jiangsu province, the prevalence of hepatitis E infection was surveyed systemically and completely through the initiatively monitoring system for the suspected cases of hepatitis E covering the city, town and village levels of medical and health serv- ice organizations. It was found that the initiatively monitoring system for suspected hepatitis E cases reflected the incidence of hepatitis E more accurately and comprehensively and was proved to be more sensitive than the network reporting system. The cases with hepatitis E accounted to 26.7% of the suspected cases with acute hepatitis and they were more frequent in male than in female. The incidence of hepatitis E increased with advance of age and most of cases occurred with age over 35. Estimated incidence was stable on the whole year, but rose up in winter and spring. The HEV type 1 and type 4 co-existed, but the HEV type 4, was proved to be the main type （92.5%）. From the above observations, it seems that the initiatively monitoring system for the suspected cases of hepatitis E may be under-estimated for the risk of the hepatitis E infection in rural area of Jiangsu province.

关 键 词：戊型肝炎 流行病学特征 基因分型 

分 类 号：R512.6[医药卫生—内科学]