正常人股骨近端骨密度变化(附445例DXA测量分析)  

Bone mineral analysis of proximal femur in 445 normal subjects assessed by dual X-ray absorptiometry

作　　者：余卫[1] 秦明伟[1] 徐苓[1] 田均平[1] 邢小平[1] 孟迅吾[1] 曹坚[1] 严洪珍[1] 葛秦生[1] 

机构地区：[1]中国医学科学院中国协和医科大学北京协和医院

出　　处：《中华放射学杂志》1998年第1期23-26,共4页Chinese Journal of Radiology

基　　金：卫生部和中国医学科学院研究基金

摘　　要：目的了解正常人股骨近端各部位骨密度变化。材料与方法采用双能Ｘ线骨密度仪测量４４５例正常人股骨近端各部位骨密度值，其中女性２５５例，平均年龄４５．７岁；男性１９０例，平均年龄４６．９岁。按１０岁一个年龄组统计分析。结果男性股骨近端各部位骨量峰值高于女性。男性各部位骨量峰值均在２０～２９岁年龄组，女性股骨颈骨量峰值位于２０～３９岁年龄组之间；Ｗａｒｄ区值位于１０～２９岁之间；大粗隆区值位于１０～１９岁年龄组。男性股骨近端骨密度在７０～７９岁年龄组也有上升趋势。女性股骨近端各部位峰值虽与欧美女性比较无明显差异（Ｐ＞０．０５），但股骨颈峰值骨量显著高于日本女性（Ｐ＜０．０５）。结论提供了正常人各年龄组股骨近端各部位骨密度的正常数据及变化特点，为股骨近端骨质疏松的研究积累了数据和资料。Purpose To understand bone mineral density (BMD) changes in normal subjects. Materials and methods BMD was measured by dual X-ray absorptiometry (DXA) at three sites (neck, Ward's triangle, greater trochanter) of the proximal femur in 445 normal volunteers. There were 255 females (mean age 45.7 years) and 190 males (mean age 46.9 years), divided into ten year cohorts for the analysis. Results Peak bone density at each site proximal femur was higher in males than that in females. In males, peak bone density ages for all sites of the proximal femur were in the 20～29 age group. In females, peak bone density ages was detected between 20～39 years for the neck, 10～29 years for the Ward's triangle and 10～19 years for the greater trochanter respectively. Bone loss for each site in females was more pronounced than in males, especially after 40～49 age group. There was a tendency of increased BMD among the 70～79 age group for males. Peak bone density of proximal femur for each site was not significantly lower in the females as compared with US/Europe. However, the peak bone density of femoral neck was higher in the females compared with the Japanese females. Conclusion This study provides the normal BMD data of the proximal femur for both males and females in the Chinese and also analyses the characteristics of the femoral BMD changes with aging, which will be helpful for osteoporotic research in the femoral region.

关 键 词：骨质疏松 股骨 骨密度 X线测量 DXA 

分 类 号：R681.04[医药卫生—骨科学] R816.8[医药卫生—外科学]