双活性液晶中间体4-(ω)-羟乙氧基苯甲酸的合成及其工艺研究  

Synthesis and Technological Investigation of Bi-activity Liquid Crystalline Intermediate- -4-(ω)-Hydroxyethoxybenzoic Acid

作　　者：武晋雅[1] 韩相恩[1] 杨立华[1] 吴玉彬[1] 刘改兰[1] 

机构地区：[1]兰州交通大学化学与生物工程学院,甘肃兰州730070

出　　处：《化工中间体》2009年第3期46-48,共3页

摘　　要：以氢氧化钠、碘化钾、2-溴乙醇以及对羟基苯甲酸为基本原料合成了4-(ω)-羟乙氧基苯甲酸,并通过正交实验讨论了反应温度和反应物用量等因素对反应产率的影响,得到了最佳合成工艺,其产率可达到90%以上。最后用IR和1H NMR将所得化合物进行了结构表征,证明所合成化合物是4-(ω)-羟乙氧基苯甲酸。The 4-（ω）-hydroxyethoxybenzoic acid has been synthesized in this article by sodium hydroxide, potassium iodide, 2-bromoethanol and p-hydroxybenzoic acid as substrates. The reaction temperature, the reaction masses of all reactants and other factors have been discussed through orthogonal experiment. The best synthesis technology of the 4-（ω）-hydroxyethoxybenzoic acid has been achieved, the synthesis yield has been beyond 90%. At the end of this article, its structure has been identified by IR and 1H NMR.

关 键 词：4-(ω)-羟乙氧基苯甲酸 合成工艺 正交实验 

分 类 号：TQ241[化学工程—有机化工]